Editing Apheresis (section)

=== Intermittent flow centrifugation ===

Intermittent flow centrifugation (IFC) works in cycles, taking blood, spinning/processing it and then giving back the unused parts to the donor in a [[Bolus (medicine)|bolus]]. The main advantage is a single venipuncture site. It does require a larger extracorporeal volume, and takes significantly longer to perform the procedure via IFC. As such, it is less likely to be used for therapeutic reasons, and is often seen in Donation Center settings.<ref>{{Cite web |title=Apheresis |url=https://www.transfusions.org/p/apheresis.html |access-date=2022-10-24 |language=en}}</ref> To stop the blood from [[Coagulation|coagulating]], [[anticoagulant]] is automatically mixed with the blood as it is pumped from the body into the apheresis machine.<ref>{{cite journal |vauthors=Vurro F, Merolle L, Marraccini C, Parisi M, Canovi L, Erta B, Santachiara A, Bonvicini L, Giorgi Rossi P, Baricchi R, Pertinhez TA |title=Quantitative assessment of the anticoagulant in plasma units collected by plasmapheresis |journal=Transfusion |volume=59 |issue=6 |pages=2113–20 |date=June 2019 |pmid=30875439 |doi=10.1111/trf.15244 }}</ref>