Editing Bronchodilator (section)

==Anticholinergics==
{{main article|Anticholinergics}}

Some examples of anticholinergics are [[tiotropium]] (Spiriva) and [[ipratropium|ipratropium bromide]].{{citation needed|date=February 2022}}

Tiotropium is a long-acting, 24-hour, anticholinergic bronchodilator used in the management of [[chronic obstructive pulmonary disease]] (COPD).

Only available as an inhalant, ipratropium bromide is used in the treatment of asthma and COPD. As a short-acting anticholinergic, it improves lung function and reduces the risk of exacerbation in people with symptomatic asthma.<ref>{{cite journal | vauthors = Price D, Fromer L, Kaplan A, van der Molen T, Román-Rodríguez M | title = Is there a rationale and role for long-acting anticholinergic bronchodilators in asthma? | journal = npj Primary Care Respiratory Medicine | volume = 24 | issue = 1 | pages = 14023 | date = July 2014 | pmid = 25030457 | doi = 10.1038/npjpcrm.2014.23 | pmc = 4373380 }}</ref> However, it will not stop an asthma attack already in progress. Because it has no effect on asthma symptoms when used alone, it is most often paired with a short-acting β<sub>2</sub>-adrenergic agonist. While it is considered a relief or rescue medication, it can take a full hour to begin working. For this reason, it plays a secondary role in acute asthma treatment. Dry throat is the most common side effect. If the medication gets in contact with the eyes, it may cause blurred vision for a brief time.

The use of anticholinergics in combination with short-acting β<sub>2</sub>-adrenergic agonists has been shown to reduce hospital admissions in children and adults with acute asthma exacerbations.<ref>{{cite journal | vauthors = Rodrigo GJ, Castro-Rodriguez JA | title = Anticholinergics in the treatment of children and adults with acute asthma: a systematic review with meta-analysis | journal = Thorax | volume = 60 | issue = 9 | pages = 740–6 | date = September 2005 | pmid = 16055613 | pmc = 1747524 | doi = 10.1136/thx.2005.040444 }}</ref><ref>{{cite journal | vauthors = Griffiths B, Ducharme FM | title = Combined inhaled anticholinergics and short-acting beta2-agonists for initial treatment of acute asthma in children | journal = Paediatric Respiratory Reviews | volume = 14 | issue = 4 | pages = 234–5 | date = December 2013 | pmid = 24070913 | doi = 10.1016/j.prrv.2013.08.002 }}</ref>