Editing Chondrosarcoma (section)

==Causes==
The cause is unknown. There may be a history of [[enchondroma]] or [[osteochondroma]]. A small minority of secondary chondrosarcomas occur in people with [[Maffucci syndrome]] and [[Ollier disease]].<ref>{{Cite journal|title = Secondary chondrosarcoma|journal = The Journal of the American Academy of Orthopaedic Surgeons|date = Oct 2010|issn = 1067-151X|pmid = 20889950|pages = 608–615|volume = 18|issue = 10|first1 = Patrick P.|last1 = Lin|first2 = Charbel D.|last2 = Moussallem|first3 = Michael T.|last3 = Deavers|doi = 10.5435/00124635-201010000-00004|s2cid = 25873835}}</ref>

It has been associated with faulty [[isocitrate dehydrogenase]] 1 and 2 enzymes, which are also associated with [[glioma]]s and [[leukemia]]s.<ref>{{Cite journal|title = IDH1 and IDH2 mutations are frequent events in central chondrosarcoma and central and periosteal chondromas but not in other mesenchymal tumours|journal = The Journal of Pathology|date = Jul 2011|issn = 1096-9896|pmid = 21598255|pages = 334–343|volume = 224|issue = 3|doi = 10.1002/path.2913|first1 = M. Fernanda|last1 = Amary|first2 = Krisztian|last2 = Bacsi|first3 = Francesca|last3 = Maggiani|first4 = Stephen|last4 = Damato|first5 = Dina|last5 = Halai|first6 = Fitim|last6 = Berisha|first7 = Robin|last7 = Pollock|first8 = Paul|last8 = O'Donnell|first9 = Anita|last9 = Grigoriadis|s2cid = 24201208|hdl = 1887/108488|hdl-access = free}}</ref>