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Cluster headache
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===Other symptoms=== The typical symptoms of cluster headache include grouped occurrence and recurrence (cluster) of headache attack, severe unilateral orbital, supraorbital and/or temporal pain. If left untreated, attack frequency may range from one attack every two days to eight attacks per day.<ref name=AFP2013/><ref name=IHS/> Cluster headache attack is accompanied by at least one of the following autonomic symptoms: [[Ptosis (eyelid)|drooping eyelid]], [[miosis|pupil constriction]], redness of the [[conjunctiva]], [[lacrimation|tearing]], [[rhinorrhea|runny nose]] and less commonly, [[facial blushing]], swelling, or sweating, typically appearing on the same side of the head as the pain.<ref name=IHS/> Similar to a migraine, sensitivity to light ([[photophobia]]) or noise ([[hyperacusis]]) may occur during a cluster headache. Nausea is a rare symptom although it has been reported.<ref name=Beck/> Restlessness (for example, pacing or rocking back and forth) may occur. Secondary effects may include the inability to organize thoughts and plans, physical exhaustion, confusion, agitation, aggressiveness, depression, and anxiety.<ref name="Rob2013"/> People with cluster headaches may dread facing another headache and adjust their physical or social activities around a possible future occurrence. Likewise they may seek assistance to accomplish what would otherwise be normal tasks. They may hesitate to make plans because of the regularity, or conversely, the [[Predictability|unpredictability]] of the pain schedule. These factors can lead to generalized [[anxiety disorder]]s, [[panic disorder]],<ref name="Rob2013"/> serious [[depressive disorder]]s,<ref>{{cite journal |doi=10.1177/0333102412469738 |pmid=23212294 |title=Cluster headache is associated with an increased risk of depression: A nationwide population-based cohort study |journal=Cephalalgia |volume=33 |issue=3 |pages=182β9 |year=2012 |last1=Liang |first1=Jen-Feng |last2=Chen |first2=Yung-Tai |last3=Fuh |first3=Jong-Ling |last4=Li |first4=Szu-Yuan |last5=Liu |first5=Chia-Jen |last6=Chen |first6=Tzeng-Ji |last7=Tang |first7=Chao-Hsiun |last8=Wang |first8=Shuu-Jiun |s2cid=23184973 |doi-access=free }}</ref> social withdrawal and isolation.<ref>{{cite journal |doi=10.1111/j.1468-2982.2007.01330.x |pmid=17459083 |title=Burden of Cluster Headache |journal=Cephalalgia |volume=27 |issue=6 |pages=535β41 |year=2016 |last1=Jensen |first1=RM |last2=Lyngberg |first2=A |last3=Jensen |first3=RH |s2cid=38485245 }}</ref> Cluster headaches have been recently associated with obstructive [[sleep apnea]] comorbidity.<ref>{{cite journal |title=Right-to-left shunt and obstructive sleep apnea in cluster headache |journal=Neurology & Neurosc. |volume=1 |issue=1 |pages=1β3 |year=2020 |last1=Tabaee D. |first1=Payam |last2=Rizzoli |first2=P |last3=Pecis |first3=M |url=https://www.sciencexcel.com/articles/Right-to-left%20shunt%20and%20obstructive%20sleep%20apnea%20in%20cluster%20headache |access-date=22 January 2021 |archive-date=24 October 2020 |archive-url=https://web.archive.org/web/20201024174835/https://www.sciencexcel.com/articles/Right-to-left%20shunt%20and%20obstructive%20sleep%20apnea%20in%20cluster%20headache |url-status=live }}</ref>
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