Editing Coloboma (section)

==Causes==
Coloboma can be associated with a mutation in the ''[[PAX2]]'' gene.<ref name="pmid9783702">{{cite journal |display-authors= 3| vauthors=Cunliffe HE, McNoe LA, Ward TA, Devriendt K, Brunner HG, Eccles MR |title=The prevalence of PAX2 mutations in patients with isolated coloboma or colobomata associated with urogenital anomalies |journal=J. Med. Genet. |volume=35 |issue=10 |pages=806–12 |date=October 1998 |pmid=9783702 |pmc=1051454 |doi= 10.1136/jmg.35.10.806}}</ref>

Eye abnormalities have been shown to occur in over 90% of children with [[fetal alcohol syndrome]].<ref>{{cite journal | pmc = 2773598 | pmid=19907681 | volume=78 | title=Eye abnormalities in fetal alcohol syndrome. | date=Sep 2009 | journal=Ulster Med J | pages=164–5| last1=Abdelrahman | first1=A. | last2=Conn | first2=R. | issue=3 }}</ref>