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Dimethyltryptamine
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====Inhalation==== [[File:N,N-DMT Freebase and Vape cartridge.jpg|thumb|[[Free base]] DMT extracted from ''[[Mimosa hostilis]]'' root bark (left); vape cartridge made with freebase DMT extract (right)]] A standard dose for vaporized DMT is 20β60 milligrams, depending highly on the efficiency of vaporization as well as body weight and personal variation.<ref>{{cite web|url=https://erowid.org/chemicals/dmt/dmt_dose.shtml|title=DMT Dosage|website=[[Erowid]]|access-date=25 June 2018|archive-date=25 June 2018|archive-url=https://web.archive.org/web/20180625185707/https://erowid.org/chemicals/dmt/dmt_dose.shtml|url-status=live}}</ref><ref name="TiHKAL" />{{medical citation needed | date = June 2023}} In general, this is inhaled in a few successive breaths, but lower doses can be used if the user can inhale it in fewer breaths (ideally one). The effects last for a short period of time, usually 5 to 15 minutes, dependent on the dose. The onset after inhalation is very fast (less than 45 seconds) and peak effects are reached within a minute. In the 1960s, DMT was known as a "businessman's trip" in the US because of the relatively short duration (and rapid onset) of action when inhaled.<ref>{{cite journal | vauthors = Haroz R, Greenberg MI | title = Emerging drugs of abuse | journal = The Medical Clinics of North America | volume = 89 | issue = 6 | pages = 1259β1276 | date = November 2005 | pmid = 16227062 | doi = 10.1016/j.mcna.2005.06.008 | quote = Use of DMT was first encountered in the United States in the 1960s, when it was known as a 'businessman's trip' because of the rapid onset of action when smoked (2 to 5 minutes) and short duration of action (20 minutes to 1 hour). | oclc = 610327022 }}</ref> DMT can be inhaled using a [[bong]], typically when sandwiched between layers of plant matter, using a specially designed pipe, or by using an [[e-cigarette]] once it has been dissolved in propylene glycol and/or vegetable glycerin.<ref>{{Cite web|vauthors=Power M|date=5 June 2020|title=I Sell DMT Vape Pens So People Can 'Break Through' at Their Own Speed|url=https://www.vice.com/en/article/i-sell-dmt-vape-pens-so-people-can-break-through-at-their-own-speed/|access-date=12 July 2020|website=Vice.com|language=en|archive-date=12 July 2020|archive-url=https://web.archive.org/web/20200712192852/https://www.vice.com/en_uk/article/akzgbz/i-sell-dmt-vape-pens-so-people-can-break-through-at-their-own-speed|url-status=live}}</ref> Some users have also started using vaporizers meant for cannabis extracts ("wax pens") for ease of temperature control when vaporizing crystals. A DMT-infused smoking blend is called [[Changa (drug)|Changa]], and is typically used in pipes or other utensils meant for smoking dried plant matter.{{cn|date=June 2023}}
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