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Epidermis
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===Cell boundaries=== Epidermal cells are tightly interconnected to serve as a tight barrier against the exterior environment. The junctions between the epidermal cells are of the [[adherens junction]] type, formed by transmembrane proteins called [[cadherins]]. Inside the cell, the cadherins are linked to [[actin]] filaments. In immunofluorescence microscopy, the actin filament network appears as a thick border surrounding the cells,<ref name="2017-Hanukoglu" /> although the [[microfilament|actin filaments]] are actually located inside the cell and run parallel to the cell membrane. Because of the proximity of the neighboring cells and tightness of the junctions, the actin [[immunofluorescence]] appears as a border between cells.<ref name="2017-Hanukoglu" />
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