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Forward genetics
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=== Radiation mutagenesis === Other methods such as using radiation to cause large deletions and [[chromosomal rearrangement]]s can be used to generate mutants as well.<ref name="parsch" /> Ionizing radiation can be used to induce genome-wide mutations as well as chromosomal duplications, inversions, and translocations. Similarly, short wave UV light works in the same way as ionizing radiation which can also induce mutations generating chromosomal rearrangements. When DNA absorbs short wave UV light, dimerizing and oxidative mutations can occur which can cause severe damage to the DNA sequence of an organism.
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