Editing Founder effect (section)

==Serial founder effect==
Serial founder effects have occurred when populations migrate over long distances. Such long-distance migrations typically involve relatively rapid movements followed by periods of settlement. The populations in each migration carry only a subset of the genetic diversity carried from previous migrations. As a result, genetic differentiation tends to increase with geographic distance as described by the "isolation by distance" model.<ref>{{cite journal |doi=10.1073/pnas.0507611102 |jstor=4143304 |pmid=16243969 |pmc=1276087 |title=Support from the relationship of genetic and geographic distance in human populations for a serial founder effect originating in Africa |journal=Proceedings of the National Academy of Sciences |volume=102 |issue=44 |pages=15942–7 |year=2005 |last1=Ramachandran |first1=S. |last2=Deshpande |first2=O. |last3=Roseman |first3=C. C. |last4=Rosenberg |first4=N. A. |last5=Feldman |first5=M. W. |last6=Cavalli-Sforza |first6=L. L. |bibcode=2005PNAS..10215942R |doi-access=free }}</ref> The migration of humans [[Recent African origin of modern humans|out of Africa]] is characterized by serial founder effects.<ref>{{cite journal |doi=10.1073/pnas.0903341106 |jstor=40485019 |pmid=19706453 |pmc=2752555 |title=Explaining worldwide patterns of human genetic variation using a coalescent-based serial founder model of migration outward from Africa |journal=Proceedings of the National Academy of Sciences |volume=106 |issue=38 |pages=16057–62 |year=2009 |last1=Degiorgio |first1=M. |last2=Jakobsson |first2=M. |last3=Rosenberg |first3=N. A. |bibcode=2009PNAS..10616057D |doi-access=free }}</ref> Africa has the highest degree of human genetic diversity of any continent, which is consistent with an African origin of modern humans.<ref>{{Cite journal |last1=Schlebusch |first1=Carina M. |last2=Jakobsson |first2=Mattias |date=2018-08-31 |title=Tales of Human Migration, Admixture, and Selection in Africa |journal=Annual Review of Genomics and Human Genetics |language=en |volume=19 |issue=1 |pages=405–428 |doi=10.1146/annurev-genom-083117-021759 |issn=1527-8204|doi-access=free |pmid=29727585 }}</ref>