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===Transcriptomes=== The [[transcriptomes]] of several types of quiescent stem cells, such as [[hematopoietic]], muscle, and hair follicle, have been characterized through [[high throughput biology|high-throughput]] techniques, such as [[microarray]] and [[RNA sequencing]]. Although variations exist in their individual transcriptomes, most quiescent tissue stem cells share a common pattern of gene expression that involves downregulation of cell cycle progression genes, such as [[cyclin A2]], [[cyclin B1]], [[cyclin E2]], and [[survivin]], and upregulation of genes involved in the regulation of transcription and stem cell fate, such as [[FOXO3]] and [[EZH1]]. Downregulation of mitochondrial [[cytochrome C]] also reflects the low metabolic state of quiescent stem cells.<ref name="CheungRando2013">{{cite journal | vauthors = Cheung TH, Rando TA | title = Molecular regulation of stem cell quiescence | journal = Nature Reviews. Molecular Cell Biology | volume = 14 | issue = 6 | pages = 329β40 | date = June 2013 | pmid = 23698583 | pmc = 3808888 | doi = 10.1038/nrm3591 }}</ref>
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