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==Facilities== [[File:Genentech Building 31.jpg|thumb|right|Building 31, one of the newer buildings at Genentech headquarters]] Genentech's corporate headquarters are in [[South San Francisco, California]] ({{Coord|37.657|-122.379|name=Genentech}}), with additional manufacturing facilities in [[Vacaville, California]]; [[Oceanside, California]]; and [[Hillsboro, Oregon]]. In March 2024, it was announced the [[Switzerland|Swiss]] pharmaceutical company, Lonza had acquired the Vacaville site from parent-company, Roche for $1.2 billion.<ref>{{Cite web |date=2024-03-20 |title=Lonza to acquire biologics site in Vacaville, US from Roche for $1.2bn - Pharmafile |url=https://pharmafile.com/news/lonza-to-acquire-biologics-site-in-vacaville-us-from-roche-for-1-2bn/ |access-date=2024-03-20 |website=pharmafile.com |language=en-GB}}</ref> In December 2006, Genentech sold its [[O Porriño|Porriño]], [[Spain]], facility to [[Lonza Group|Lonza]] and acquired an exclusive right to purchase Lonza's mammalian cell culture manufacturing facility under construction in [[Singapore]]. In June 2007, Genentech began the construction and development of an ''E. coli'' manufacturing facility, also in Singapore, for the worldwide production of [[Lucentis]] ([[ranibizumab]] injection) bulk drug substance.{{Citation needed|date=February 2020}} In 2023, the company announced plans to close down its manufacturing facility in South San Francisco, while expanding its manufacturing capabilities in Oceanside.<ref>{{cite news |last=Varian |first=Ethan |date=March 25, 2023 |title=Genentech lays off 265 workers in South San Francisco, closes manufacturing plant |url=https://www.mercurynews.com/2023/03/25/genentech-lays-off-265-workers-in-south-san-francisco-closes-manufacturing-plant/ |newspaper=[[The Mercury News]]}}</ref><ref>{{cite news |last=Rocha |first=Natalie |date=February 21, 2023 |title=Genentech expands in Oceanside with $450M biotech manufacturing facility and 150 jobs |url=https://www.sandiegouniontribune.com/business/story/2023-02-21/genentech-expands-in-oceanside-with-450m-biotech-manufacturing-facility |newspaper=[[The San Diego Union-Tribune]]}}</ref>
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