Editing Isolobal principle (section)

===MO theory dependence===
Any sort of saturated molecule can be the starting point for generating isolobal fragments.<ref name=Gispert>{{cite book|first1=Joan Ribas |last1=Gispert|publisher=Wiley-VCH|title=Coordination Chemistry|year=2008|pages=172–176}}</ref><ref name=Atkins>{{cite book|last1=Shriver |first1=D.F. |last2=Atkins |first2=P.|author-link2 = Peter Atkins|last3=Overton |first3=T. |last4=Rourke |first4=J.|last5=Weller |first5=M.|last6=Armstrong |first6=F.|publisher=Freeman|title=Inorganic Chemistry|year=2006}}</ref> The molecule's bonding and nonbonding molecular orbitals (MOs) should be filled and the antibonding MOs empty. With each consecutive generation of an isolobal fragment, electrons are removed from the bonding orbitals and a frontier orbital is created. The frontier orbitals are at a higher energy level than the bonding and nonbonding MOs. Each frontier orbital contains one electron. For example, consider Figure 5, which shows the production of frontier orbitals in tetrahedral and octahedral molecules.

[[Image:NewFigure5.png|thumb|570px|center|'''Figure 5:''' Molecular orbital diagram depiction of frontier orbitals in methane and a basic ML<sub>6</sub> metal complex]]

As seen above, when a fragment is formed from CH<sub>4</sub>, one of the sp<sup>3</sup> [[hybrid orbitals]] involved in bonding becomes a nonbonding singly occupied frontier orbital. The frontier orbital’s increased energy level is also shown in the figure. Similarly when starting with a metal complex such as d<sup>6</sup>-ML<sub>6</sub>, the d<sup>2</sup>sp<sup>3</sup> hybrid orbitals are affected. Furthermore, the t<sub>2g</sub> nonbonding metal orbitals are unaltered.