Editing Linalool (section)

===Biosynthesis===
In [[Vascular plant|higher plants]] linalool is formed by rearrangement of [[geranyl pyrophosphate]] (GPP).<ref name="Planta Medica">{{cite journal | vauthors = Woronuk G, Demissie Z, Rheault M, Mahmoud S | title = Biosynthesis and therapeutic properties of Lavandula essential oil constituents | journal = Planta Medica | volume = 77 | issue = 1 | pages = 7–15 | date = January 2011 | pmid = 20665367 | doi = 10.1055/s-0030-1250136 | doi-access = free | bibcode = 2011PlMed..77....7W }}</ref> With the aid of [[linalool synthase (disambiguation)|linalool synthase]] (LIS), water attacks to form the chiral center.<ref>{{cite book |last1=Dewick |first1=Paul M | name-list-style = vanc |title=Medicinal Natural Products: A Biosynthetic Approach |date=2009 |publisher=John Wiley & Sons |isbn=978-0-470-74168-9 |edition=3rd}}</ref><ref name="Planta Medica"/> LIS appears to show a [[limonene synthase (disambiguation)|limonene synthase]]-type catalysis through a simplified "metal-cofactor-binding domain [where the majority] of the residues involved in substrate...binding [are] in the C-terminal part of the protein" suggesting [[stereoselectivity]] and the reasoning behind why some plants have varying levels of each enantiomer.<ref name="Molecular Biology and Evolution">{{cite journal | vauthors = Cseke L, Dudareva N, Pichersky E | title = Structure and evolution of linalool synthase | journal = Molecular Biology and Evolution | volume = 15 | issue = 11 | pages = 1491–8 | date = November 1998 | pmid = 12572612 | doi = 10.1093/oxfordjournals.molbev.a025876 | doi-access = free }}</ref><ref name="Plant Physiol">{{cite journal | vauthors = Iijima Y, Davidovich-Rikanati R, Fridman E, Gang DR, Bar E, Lewinsohn E, Pichersky E | title = The biochemical and molecular basis for the divergent patterns in the biosynthesis of terpenes and phenylpropenes in the peltate glands of three cultivars of basil | journal = Plant Physiology | volume = 136 | issue = 3 | pages = 3724–36 | date = November 2004 | pmid = 15516500 | pmc = 527170 | doi = 10.1104/pp.104.051318 | doi-access = free }}</ref>
[[File:Linalool_Biosynthesis.png|alt=|center|thumb|Linalool [[biosynthesis]] [[metabolic pathway|pathway]]. Abbreviations used: geranyl diphosphate synthase (GDS), pyrophosphate ester (OPP), [[isopentenyl pyrophosphate]] (IPP), [[dimethylallyl pyrophosphate]] (DMAPP), geranyl pyrophosphate (GPP). Stereogenic centers are indicated by an asterisk.|654x654px]]