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Methylphenidate
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=== Narcolepsy === [[Narcolepsy]], a [[chronic condition|chronic]] [[sleep disorder]] characterized by overwhelming daytime drowsiness and uncontrollable sleep, is treated primarily with stimulants. Methylphenidate is considered effective in increasing [[wakefulness]], vigilance, and performance.<ref name="pmid9484423">{{cite journal | vauthors = Fry JM | title = Treatment modalities for narcolepsy | journal = Neurology | volume = 50 | issue = 2 Suppl 1 | pages = S43βS48 | date = February 1998 | pmid = 9484423 | doi = 10.1212/WNL.50.2_Suppl_1.S43 | s2cid = 36824088 }}</ref> Methylphenidate improves measures of [[somnolence]] on [[medical test|standardized tests]], such as the [[Multiple Sleep Latency Test]] (MSLT), but performance does not improve to levels comparable to healthy people.<ref name="pmid7701190">{{cite journal | vauthors = Mitler MM | title = Evaluation of treatment with stimulants in narcolepsy | journal = Sleep | volume = 17 | issue = 8 Suppl | pages = S103βS106 | date = December 1994 | pmid = 7701190 | doi = 10.1093/sleep/17.suppl_8.S103 | doi-access = free }}</ref>
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