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Myocarditis
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=== Infections === The most common causes of myocarditis are infectious organisms. Viral infections are the most common cause in developed countries, with a majority of cases being caused by those with single-stranded RNA genomes, such as Coxsackie viruses (especially Coxsackie B3 and B5).<ref name=":0">{{Cite book| vauthors = Marín-García J |title=Post-Genomic Cardiology|publisher=Academic Press|year=2007|isbn=978-0-12-373698-7 |pages=416|name-list-style=vanc}}</ref><ref name=":10">{{cite journal | vauthors = Rose NR | title = Viral myocarditis | journal = Current Opinion in Rheumatology | volume = 28 | issue = 4 | pages = 383–389 | date = July 2016 | pmid = 27166925 | pmc = 4948180 | doi = 10.1097/BOR.0000000000000303 }}</ref> Globally, [[Chagas disease]] is the leading cause of myocarditis, which results from infection with the [[protozoa]]n ''[[Trypanosoma cruzi]].''<ref name="Feldman" /> Bacteria can also result in myocarditis, although it is rare in patients with normal heart function and without a preexisting [[immunodeficiency]].<ref name=":11" /><ref>{{cite journal | vauthors = Piccirillo F, Watanabe M, Di Sciascio G | title = Diagnosis, treatment and predictors of prognosis of myocarditis. A narrative review | journal = Cardiovascular Pathology | volume = 54 | pages = 107362 | date = September 2021 | pmid = 34192559 | doi = 10.1016/j.carpath.2021.107362 }}</ref> A list of the most relevant infectious organisms is below. * Viral: [[adenovirus]], [[parvovirus B19]], [[coxsackie virus]], [[rubella virus]], [[polio virus]], [[Epstein-Barr virus]], hepatitis C virus, [[influenza virus]]<ref>{{cite journal |last1=Estabragh |first1=ZR |last2=Mamas |first2=MA |title=The cardiovascular manifestations of influenza: a systematic review. |journal=International Journal of Cardiology |date=10 September 2013 |volume=167 |issue=6 |pages=2397–403 |doi=10.1016/j.ijcard.2013.01.274 |pmid=23474244}}</ref> and [[severe acute respiratory syndrome coronavirus 2]] (SARS‑CoV‑2, causing [[COVID-19]])<ref>{{cite journal | vauthors = Andréoletti L, Lévêque N, Boulagnon C, Brasselet C, Fornes P | title = Viral causes of human myocarditis | journal = Archives of Cardiovascular Diseases | volume = 102 | issue = 6–7 | pages = 559–568 | date = June 2009 | pmid = 19664576 | doi = 10.1016/j.acvd.2009.04.010 | doi-access = free }}</ref><ref>{{cite book | vauthors = Sheppard M |title=Practical Cardiovascular Pathology |edition=2nd |date=2011 |publisher=CRC Press |isbn=978-0-340-98193-1 |page=197 |url=https://books.google.com/books?id=W2u-vNQ4Wy8C&pg=PA197 }}</ref><ref name=":5">{{cite journal | vauthors = Rathore SS, Rojas GA, Sondhi M, Pothuru S, Pydi R, Kancherla N, Singh R, Ahmed NK, Shah J, Tousif S, Baloch UT, Wen Q | display-authors = 6 | title = Myocarditis associated with Covid-19 disease: A systematic review of published case reports and case series | journal = International Journal of Clinical Practice | volume = 75 | issue = 11 | pages = e14470 | date = November 2021 | pmid = 34235815 | doi = 10.1111/ijcp.14470 | s2cid = 235768792 | doi-access = free }}</ref> * Protozoan: ''Trypanosoma cruzi'' and ''[[Toxoplasma gondii]]'' (causing Chagas disease and toxoplasmosis, respectively)<ref name="Feldman" /><ref>{{cite journal | vauthors = Zhou Z, Ortiz Lopez HI, Pérez GE, Burgos LM, Farina JM, Saldarriaga C, Lopez-Santi R, Cotella JI, Pérez AL, Baranchuk A | display-authors = 6 | title = Toxoplasmosis and the Heart | journal = Current Problems in Cardiology | volume = 46 | issue = 3 | pages = 100741 | date = March 2021 | pmid = 33183832 | doi = 10.1016/j.cpcardiol.2020.100741 | s2cid = 226850411 }}</ref> * Bacterial: [[brucellosis|''Brucella'']], ''[[Corynebacterium diphtheriae]]'', ''[[Neisseria gonorrhoeae]]'', ''[[Haemophilus influenzae]]'', ''[[Actinomyces]]'', ''[[Whipple's disease|Tropheryma whipplei]]'', ''[[Vibrio cholerae]]'', ''[[Borrelia burgdorferi]]'', [[leptospirosis|''Leptospira'']], ''[[Rickettsia]]'', ''[[Mycoplasma pneumoniae]]'' * Fungal: ''[[Aspergillus]]'' * Parasitic: ''[[Ascaris]]'', ''[[Echinococcus granulosus]]'', ''[[Paragonimus westermani]]'', ''[[Schistosoma]]'', ''[[Taenia solium]]'', ''[[Trichinella spiralis]]'', [[visceral larva migrans]], ''[[Wuchereria bancrofti]]''
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