Editing Nasal polyp (section)

==Pathophysiology==
The true cause of nasal polyps is unknown, but they are thought to be due to recurrent infection or inflammation.<ref name="Zit2018" /> Polyps arise from the lining of the sinuses. Nasal mucosa, particularly in the region of [[middle meatus]] becomes swollen due to collection of extracellular fluid. This extracellular fluid collection causes polyp formation and protrusion into the nasal cavity or sinuses. Polyps which are sessile in the beginning become [[Peduncle (anatomy)|pedunculated]] due to gravity.<ref>{{Cite book |last=Wilkins |first=Lippincott Williams & |url=https://archive.org/details/isbn_9780781778992 |title=Professional Guide to Diseases |date=2009 |publisher=Lippincott Williams & Wilkins |isbn=9780781778992 |page=[https://archive.org/details/isbn_9780781778992/page/n734 717] |language=en |url-access=registration}}</ref>

In people with nasal polyps due to [[aspirin]] or [[NSAID]] sensitivity, the underlying mechanism is due to disorders in the metabolism of [[arachidonic acid]]. Exposure to [[cycloxygenase inhibitors]] such as aspirin and NSAIDs leads to shunting of products through the lipoxygenase pathway leading to an increased production of products that cause inflammation. In the airway, these inflammatory products lead to symptoms of asthma such as wheezing as well as nasal polyp formation.<ref name="Cour2016">{{Cite book |last=Courey |first=Mark |title=Upper Airway Disorders |date=2016 |publisher=Elsevier Saunders |isbn=978-1455733835 |pages=877–896}}</ref>