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Native state
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===Nucleic acids=== Nucleic acids attain their native state through [[base pair]]ing and, to a lesser extent, other interactions such as [[coaxial stacking]]. Biological [[DNA]] usually exists as long linear [[Nucleic acid double helix|double helices]] bound to proteins in [[chromatin]], and biological [[RNA]] such as [[tRNA]] often form complex native configurations approaching the complexity of folded proteins. Additionally, artificial nucleic acid structures used in [[DNA nanotechnology]] are designed to have specific native configurations in which multiple nucleic acid strands are assembled into a single complex. In some cases native state of biological DNA performs their functions without being controlled by any other regulatory units.
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