Editing Neomycin (section)

===Spectrum===
Similar to other aminoglycosides, neomycin has excellent activity against [[Gram-negative bacteria]] and is partially effective against [[Gram-positive bacteria]]. It is relatively toxic to humans, with allergic reactions noted as a common adverse reaction (see: [[hypersensitivity]]).<ref>{{DermNet|dermatitis/neomycin-allergy}}</ref> Physicians sometimes recommend using antibiotic ointments without neomycin, such as [[Polysporin]].<ref>{{cite web |url=http://www.dermadoctor.com/article_Your-Medicine-Cabinet_43.html |title=Your Medicine Cabinet |publisher=DERMAdoctor.com, Inc. |access-date=2008-10-19 |url-status=dead |archive-url=https://web.archive.org/web/20090709093022/http://www.dermadoctor.com/article_Your-Medicine-Cabinet_43.html |archive-date=2009-07-09}}</ref> The following represents [[minimum inhibitory concentration]] (MIC) susceptibility data for a few medically significant Gram-negative bacteria.<ref>{{cite web |url=http://www.toku-e.com/Assets/MIC/Neomycin%20sulfate%20EP.pdf |title=Neomycin sulfate, EP Susceptibility and Minimum Inhibitory Concentration (MIC) Data |publisher=TOKU-E |access-date=2014-03-31 |archive-date=2015-12-22 |archive-url=https://web.archive.org/web/20151222095539/http://www.toku-e.com/Assets/MIC/Neomycin%20sulfate%20EP.pdf |url-status=live }}</ref>
* ''Enterobacter cloacae'': >16 μg/ml
* ''Escherichia coli'': 1 μg/ml
* ''Proteus vulgaris'': 0.25 μg/ml