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Neuroblast
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===Migration=== In the [[embryo]] neuroblasts form the middle '''mantle layer''' of the [[neural tube]] wall which goes on to form the [[grey matter]] of the [[spinal cord]]. The outer layer to the mantle layer is the '''marginal layer''' and this contains the myelinated axons from the neuroblasts forming the [[white matter]] of the spinal cord.<ref name="Sadler"/> The inner layer is the [[ependyma|ependymal layer]] that will form the lining of the [[ventricular system|ventricles]] and [[central canal]] of the spinal cord.<ref name="Tortora">{{cite book |last1=Tortora |first1=G |last2=Derrickson |first2=B |title=Principles of anatomy & physiology. |date=2011 |publisher=Wiley |isbn=9780470646083 |page=571 |edition=13th.}}</ref> In humans, neuroblasts produced by stem cells in the adult [[subventricular zone]] [[cell migration|migrate]] into damaged areas after brain injuries. However, they are restricted to the subtype of small interneuron-like cells, and it is unlikely that they contribute to functional recovery of [[Striatum|striatal]] circuits.<ref name="Liu">{{cite journal | last1=Liu | first1=F | title=Brain Injury Does Not Alter the Intrinsic Differentiation Potential of Adult Neuroblasts | journal=The Journal of Neuroscience | volume=29 | issue=16 | pages=5075β5087 |date=April 2009 | doi=10.1523/JNEUROSCI.0201-09.2009 | pmid=19386903 | last2=You | first2=Y | last3=Li | first3=X | last4=Ma | first4=T | last5=Nie | first5=Y | last6=Wei | first6=B | last7=Li | first7=T | last8=Lin | first8=H | last9=Yang | first9=Z | pmc=6665479 | doi-access=free }}</ref>
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