Editing Nutrient sensing (section)

==Regulation of tissue growth==

Nutrient sensing is a key regulator of tissue growth. The main mediator of cellular nutrient sensing is the protein kinase [[MTOR|TOR (target of rapamycin)]]. TOR receives information from levels of cellular [[amino acid]]s and energy, and it regulates the activity of processes involved in cell growth, such as protein synthesis and autophagy. Insulin-like signaling is the main mechanism of systemic nutrient sensing and mediates its growth-regulatory functions largely through the protein kinase pathway. Other nutrition-regulated hormonal mechanisms contribute to growth control of modulating the activity of insulin-like signaling.<ref>{{cite journal |pmid=19694515 | doi=10.1146/annurev-genet-102108-134815 | volume=43 | title=Regulation of tissue growth through nutrient sensing | year=2009 | journal=Annu. Rev. Genet. | pages=389–410 | last1 = Hietakangas | first1 = V | last2 = Cohen | first2 = SM}}</ref>