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Pathophysiology
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===Early Developments=== The origins of pathophysiology as a distinct field date back to the late 18th century. The first known lectures on the subject were delivered by Professor {{interlanguage link|August Friedrich Hecker|de}} at the [[University of Erfurt]] in 1790, and in 1791, he published the first textbook on pathophysiology, ''Grundriss der Physiologia pathologica'',<ref>{{cite book |last1=Hecker |first1=August Friedrich |title=Grundriss der Physiologia pathologica, oder die Lehre von dem Bau, von der Mischung, und von den Verrichtungen des menschlichen Körpers und seiner Theile im widernatürlichen Zustande |date=1791 |volume=I |url=https://books.google.com/books?id=AM5vSxseazMC&pg=PR1 |language=de}}</ref> spanning 770 pages.<ref>{{cite journal |last1=Stoyanov |first1=George S |last2=Naskovska |first2=Galina |last3=Lyutfi |first3=Emran |last4=Kirneva |first4=Rumiana |last5=Bratoeva |first5=Kameliya |title=In Search of the Ninth Discipline: The History of Pathophysiology, with an Emphasis on Pathophysiology in Varna, Bulgaria—Celebrating 100 Years of Pathophysiology in Bulgaria |journal=Cureus |date=2 April 2018 |page=2 |doi=10.7759/cureus.2404 |doi-access=free|pmid=29872585 |pmc=5984271 }}</ref> Hecker also established the first academic journal in the field, ''Magazin für die pathologische Anatomie und Physiologie'', in 1796.<ref name="Churilov_2015">{{cite journal |last1=Churilov |first1=L. P. |date=December 2015 |title=From Physiology of Disease to Systemic Pathobiology: History and Current Trends in Pathophysiology. |url=https://www.psychiatria-danubina.com/UserDocsImages/pdf/dnb_vol27_sup2/dnb_vol27_sup2_550.pdf |journal=Psychiatria Danubina |volume=27 Suppl 2 |pages=550–570 |pmid=26657983 |archive-url=https://web.archive.org/web/20240802174614/https://www.psychiatria-danubina.com/UserDocsImages/pdf/dnb_vol27_sup2/dnb_vol27_sup2_550.pdf |archive-date=August 2, 2024}}</ref> The French physician [[Jean François Fernel]] had earlier suggested in 1542 that a distinct branch of physiology should study the functions of diseased organisms, an idea further developed by {{interlanguage link|Jean Varandal|de}} in 1617, who first coined the term "pathologic physiology" in a medical text.<ref name=Churilov_2015/>
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