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Polyuria
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==Mechanism== Polyuria, in osmotic cases, increases flow amount in the distal [[nephron]] where flow rates and [[velocity]] are low. The significant pressure increase occurring in the distal nephron takes place particularly in the cortical-collecting ducts. One study from 2008 laid out a hypothesis that hyperglycaemic and osmotic polyuria play roles ultimately in diabetic nephropathy.<ref>{{Cite journal |last=Wang |first=Shinong |last2=Mitu |first2=Grace M. |last3=Hirschberg |first3=Raimund |date=2008-07-01 |title=Osmotic polyuria: an overlooked mechanism in diabetic nephropathy |journal=Nephrology Dialysis Transplantation |volume=23 |issue=7 |pages=2167β2172 |doi=10.1093/ndt/gfn115 |issn=0931-0509 |pmid=18456680 |doi-access=free}}</ref>
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