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Promethazine
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==Overdose== Promethazine in [[overdose]] can produce signs and symptoms including [[CNS depression]], [[hypotension]], [[respiratory depression]], [[unconsciousness]], and sudden death.<ref name="Phenergan-Label">{{Cite web |title=Phenergan |url=https://www.accessdata.fda.gov/drugsatfda_docs/label/2004/07935s030lbl.pdf |archive-url=https://web.archive.org/web/20090818052606/http://www.accessdata.fda.gov/drugsatfda_docs/label/2004/07935s030lbl.pdf |url-status=dead |archive-date=18 August 2009 |access-date=30 September 2023 |website=www.accessdata.fda.gov}}</ref> Other reactions may include [[hyperreflexia]], [[hypertonia]], [[ataxia]], [[athetosis]], and [[plantar reflex|extensor-plantar reflex]]es.<ref name="Phenergan-Label" /> Atypically and/or rarely, [[stimulant|stimulation]], [[convulsion]]s, hyperexcitability, and [[nightmare]]s may occur.<ref name="Phenergan-Label" /> [[Anticholinergic]] effects like [[dry mouth]], [[dilated pupils]], [[Flushing (physiology)|flushing]], [[gastrointestinal]] symptoms, and [[delirium]] may occur as well.<ref name="Phenergan-Label" /> Treatment of overdose is supportive and based on symptoms.<ref name="Phenergan-Label" />
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