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Propofol
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===Routine procedural sedation=== Propofol is safe and effective for gastrointestinal endoscopy procedures (colonoscopies etc.). Its use in these settings results in a faster recovery compared to [[midazolam]].<ref name="McQuaid-2008">{{cite journal |vauthors=McQuaid KR, Laine L |date=May 2008 |title=A systematic review and meta-analysis of randomized, controlled trials of moderate sedation for routine endoscopic procedures |journal=Gastrointestinal Endoscopy |volume=67 |issue=6 |pages=910–923 |doi=10.1016/j.gie.2007.12.046 |pmid=18440381}}</ref> It can also be combined with [[opioids]] or [[benzodiazepines]].<ref>Canadian National Formulary 2010</ref><ref>{{cite book |title=Appleton & Lange's 1999 drug guide |vauthors=Shannon MT, Wilson BA, Stang CL |date=1999 |publisher=Appleton & Lange |isbn=978-0-8385-0371-3 |location=Stamford, CT}}</ref><ref>Numorphan® (oxymorphone) package insert (English), Endo 2009</ref> Because of its rapid induction and recovery time, propofol is also widely used for sedation of infants and children undergoing [[MRI]] procedures.<ref>{{cite journal |vauthors=Machata AM, Willschke H, Kabon B, Kettner SC, Marhofer P |date=August 2008 |title=Propofol-based sedation regimen for infants and children undergoing ambulatory magnetic resonance imaging |journal=British Journal of Anaesthesia |volume=101 |issue=2 |pages=239–243 |doi=10.1093/bja/aen153 |pmid=18534971 |doi-access=free}}</ref> It is also often used in combination with [[ketamine]] with minimal side effects.<ref>{{cite journal |vauthors=Yan JW, McLeod SL, Iansavitchene A |date=September 2015 |title=Ketamine-Propofol Versus Propofol Alone for Procedural Sedation in the Emergency Department: A Systematic Review and Meta-analysis |journal=Academic Emergency Medicine |volume=22 |issue=9 |pages=1003–1013 |doi=10.1111/acem.12737 |pmid=26292077 |doi-access=free}}</ref>
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