Editing Quasispecies model (section)

===Application to biological research===

Quasispecies represents the evolution of high-mutation-rate viruses such as [[HIV]] and sometimes single genes or molecules within the genomes of other organisms.<ref>{{cite book | vauthors = Holland JJ, De La Torre JC, Steinhauer DA | title = Genetic Diversity of RNA Viruses | chapter = RNA Virus Populations as Quasispecies | series = Current Topics in Microbiology and Immunology | volume = 176 | pages = 1–20 | pmid = 1600747 | year = 1992 | doi = 10.1007/978-3-642-77011-1_1 | isbn = 978-3-642-77013-5 | s2cid = 46530529 | doi-access = free }}</ref><ref>{{cite journal | vauthors = Shuman LJ, Wolfe H, Whetsell GW, Huber GA | title = Reimbursement alternatives for home health care | journal = Inquiry: A Journal of Medical Care Organization, Provision and Financing| volume = 13 | issue = 3 | pages = 277–87 | date = September 1976 | pmc =  | doi =  | pmid = 135734 }}</ref><ref>{{cite journal | vauthors = Wilke CO | title = Quasispecies theory in the context of population genetics | journal = BMC Evolutionary Biology | volume = 5 | pages = 44 | date = August 2005 | issue = 1 | pmid = 16107214 | pmc = 1208876 | doi = 10.1186/1471-2148-5-44 | doi-access = free | bibcode = 2005BMCEE...5...44W }}</ref> Quasispecies models have also been proposed by Jose Fontanari and [[Emmanuel David Tannenbaum]] to model the evolution of sexual reproduction.<ref>{{cite journal | vauthors = Tannenbaum E, Fontanari JF | title = A quasispecies approach to the evolution of sexual replication in unicellular organisms | journal = Theory in Biosciences | volume = 127 | issue = 1 | pages = 53–65 | date = March 2008 | pmid = 18286313 | doi = 10.1007/s12064-008-0023-2 | s2cid = 8741998 }}</ref> Quasispecies was also shown in compositional replicators (based on the [[Gard model]] for [[abiogenesis]])<ref>{{cite journal | vauthors = Gross R, Fouxon I, Lancet D, Markovitch O | title = Quasispecies in population of compositional assemblies | journal = BMC Evolutionary Biology | volume = 14 | pages = 265 | date = December 2014 | issue = 1 | pmid = 25547629 | pmc = 4357159 | doi = 10.1186/s12862-014-0265-1 | doi-access = free | bibcode = 2014BMCEE..14..265G }}</ref> and was also suggested to be applicable to describe cell's replication, which amongst other things requires the maintenance and evolution of the internal composition of the parent and bud.