Editing Quinoline (section)

== Applications ==
Quinolines are used in the manufacture of [[dye]]s and the preparation of [[hydroxyquinoline]] sulfate and [[niacin (substance)|niacin]]. It is also used as a solvent for [[resin]]s and [[terpene]]s.

Quinoline is mainly used as in the production of other [[specialty chemicals]].  Approximately 4 [[tonne]]s were produced annually according to a report published in 2005.<ref name=Hoke/>  Its principal use is as a precursor to [[8-hydroxyquinoline]], which is a versatile chelating agent and precursor to pesticides.  Its [[quinaldine|2-]] and [[lepidine|4-methyl]] derivatives are precursors to [[cyanine dye]]s.  Oxidation of quinoline affords [[quinolinic acid]] (pyridine-2,3-dicarboxylic acid), a precursor to the herbicide sold under the name "Assert".<ref name=Hoke>{{Ullmann | author1 = Gerd Collin | author2 = Hartmut Höke | title = Quinoline and Isoquinoline | doi = 10.1002/14356007.a22_465}}</ref>

The reduction of quinoline with [[sodium borohydride]] in the presence of [[acetic acid]] is known to produce [[Kairoline A]].<ref name="GRIBBLEHEALD1975">{{cite journal|last1=GRIBBLE|first1=Gordon W.|last2=HEALD|first2=Peter W.|title=Reactions of Sodium Borohydride in Acidic Media; III. Reduction and Alkylation of Quinoline and Isoquinoline with Carboxylic Acids|journal=Synthesis|volume=1975|issue=10|year=1975|pages=650–652|issn=0039-7881|doi=10.1055/s-1975-23871}}</ref> (Cf. [[Kairine]])

Several [[Antimalarial medication|anti-malarial]] drugs contain quinoline substituents.  These include [[Antimalarial medication#Quinine and related agents|quinine]], [[Antimalarial medication#Chloroquine|chloroquine]], [[Antimalarial medication#Amodiaquine|amodiaquine]], and [[Antimalarial medication#Primaquine|primaquine]].

Quinoline is used as a solvent and reagent in organic synthesis.<ref>{{cite book |doi=10.1002/047084289X.rq002.pub2 |chapter=Quinoline |title=Encyclopedia of Reagents for Organic Synthesis |year=2001 |last1=Sherman |first1=Angela R. |last2=Caron |first2=Antoine |last3=Collins |first3=Shawn K. |pages=1–4 |isbn=9780470842898 }}</ref>

Quinolinium compounds (e.g. salts) can also be used as corrosion inhibitors and intensifiers.