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Robertsonian translocation
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==Nomenclature== [[File:Human karyotype with bands and sub-bands.png|thumb|300px|Human [[karyotype]] with annotated bands and sub-bands as used for the nomenclature of chromosome abnormalities. It shows dark and white regions as seen on [[G banding]]. Each row is vertically aligned at [[centromere]] level. It shows 22 [[Homologous chromosome|homologous]] [[autosomal]] chromosome pairs, both the female (XX) and male (XY) versions of the two [[sex chromosome]]s, as well as the [[human mitochondrial genetics|mitochondrial genome]] (at bottom left). {{further|Karyotype}}]] The [[International System for Human Cytogenomic Nomenclature]] (ISCN) is an international standard for [[human chromosome]] [[nomenclature]], which includes band names, symbols and abbreviated terms used in the description of human chromosome and chromosome abnormalities. Abbreviations include ''rob'' for Robertsonian translocations.<ref>{{cite web|url=https://www.coriell.org/0/sections/support/global/iscn_help.aspx?PgId=263|title=ISCN Symbols and Abbreviated Terms|website=Coriell Institute for Medical Research|accessdate=2022-10-27}}</ref> For example, rob(21;21)(q10;q10) causes [[Down syndrome]].<ref name="Rajasekhar Rekharao Shetty Gopinath 2010 pp. 49β55">{{cite journal | last1=Rajasekhar | first1=M. | last2=Rekharao | first2=R. Murugesan | last3=Shetty | first3=H. | last4=Gopinath | first4=P. M. | last5=Satyamoorthy | first5=K. | title=Cytogenetic Analysis of 1400 Referral Cases: Manipal Experience | journal=International Journal of Human Genetics | publisher=Kamla Raj Enterprises | volume=10 | issue=1β3 | year=2010 | issn=0972-3757 | doi=10.1080/09723757.2010.11886084 | pages=49β55| s2cid=55971437 }}</ref>
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