Editing Rotavirus (section)

=== Structure ===
The [[genome]] of rotaviruses consists of 11 unique double helix molecules of [[RNA]] (dsRNA) which are 18,555 nucleotides in total. Each helix, or segment, is a [[gene]], numbered 1 to 11 by decreasing size. Each gene codes for one [[protein]], except genes 9, which codes for two.<ref name="pmid2556635">{{cite journal |vauthors=Estes MK, Cohen J |title=Rotavirus gene structure and function |journal=Microbiological Reviews |volume=53 |issue=4 |pages=410–449 |year=1989 |pmid=2556635 |pmc=372748 |doi= 10.1128/MMBR.53.4.410-449.1989}}</ref> The RNA is surrounded by a three-layered [[truncated icosahedron|icosahedral]] protein [[capsid]]. Viral particles are up to 76.5{{nbsp}}nm in diameter<ref name="pmid16913048">{{cite book |veditors=Roy P |vauthors=Pesavento JB, Crawford SE, Estes MK, Prasad BV |chapter=Rotavirus proteins: structure and assembly |volume=309 |pages=189–219 |year=2006 |pmid=16913048 |doi=10.1007/3-540-30773-7_7 |series=Current Topics in Microbiology and Immunology |title=Reoviruses: Entry, Assembly and Morphogenesis |isbn=978-3-540-30772-3|publisher=Springer|location=New York|s2cid=11290382 }}</ref><ref name="pmid8050286">{{cite book |vauthors=Prasad BV, Chiu W |chapter=Structure of Rotavirus |veditors=Ramig RF |series=Current Topics in Microbiology and Immunology|title=Rotaviruses |volume=185 |pages=9–29 |year=1994 |pmid=8050286|publisher=Springer|location=New York|isbn=978-3-540-56761-5}}</ref> and are not [[viral envelope|enveloped]].<ref name="pmid31317495">{{cite book |vauthors=Rodríguez JM, Luque D |title=Physical Virology |chapter=Structural Insights into Rotavirus Entry |series=Advances in Experimental Medicine and Biology |volume=1215|pages=45–68 |date=2019 |pmid=31317495 |doi=10.1007/978-3-030-14741-9_3|hdl=20.500.12105/10344 |isbn=978-3-030-14740-2 |s2cid=197541267 |hdl-access=free }}</ref>