Editing Small RNA (section)

==In plants==
The first known function in plants was discovered in mutants of ''[[Arabidopsis thaliana#Use as a model organism|Arabidopsis]]''. Specifically with decline in function [[mutation]]s for [[RNA-dependent RNA polymerase]] and [[DICER-like]] production. This impairment actually enhanced ''Arabidopsis'' [[plant disease resistance|resistance]] against ''[[Heterodera schachtii]]'' and ''[[Meloidogyne javanica]]''. Similarly, mutants with reduced [[Argonaute]] function - ''[[ago1-25]]'', ''[[ago1-27]]'', ''[[ago2-1]]'', and combined mutants with ''ago1-27'' and ''ago2-1'' - had greater resistance to ''[[Meloidogyne incognita]]''. Altogether this demonstrates great dependence of [[nematode]] parasitism on plants' own small RNAs.<ref name="Hewezi-2020">{{cite journal | vauthors = Hewezi T | title=Epigenetic Mechanisms in Nematode–Plant Interactions | journal=[[Annual Review of Phytopathology]] | publisher=[[Annual Reviews (publisher)|Annual Reviews]] | volume=58 | issue=1 | date=2020-08-25 | issn=0066-4286 | doi=10.1146/annurev-phyto-010820-012805 | pages=119–138| pmid=32413274 | bibcode=2020AnRvP..58..119H | s2cid=218658491 }}</ref>