Editing Spliceosome (section)

==Alternative splicing==
{{main|Alternative splicing}}
Alternative splicing (the re-combination of different [[exon]]s) is a major source of [[genetic diversity]] in eukaryotes. [[Splice variant]]s have been used to account for the relatively small number of protein coding [[gene]]s in the [[human genome]], currently estimated at around 20,000. One particular [[Drosophila]] gene, [[Dscam]], has been speculated to be alternatively spliced into 38,000 different [[mRNA]]s, assuming all of its exons can splice independently of each other.<ref name=Schmucker2000>{{cite journal | vauthors = Schmucker D, Clemens JC, Shu H, Worby CA, Xiao J, Muda M, Dixon JE, Zipursky SL | title = Drosophila Dscam is an axon guidance receptor exhibiting extraordinary molecular diversity | journal = Cell | volume = 101 | issue = 6 | pages = 671–84 | date = June 2000 | pmid = 10892653 | doi = 10.1016/S0092-8674(00)80878-8 | doi-access = free }}</ref>