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Steatorrhea
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===Medications=== [[Orlistat]] (also known by trade names Xenical and Alli) is a diet pill that works by blocking [[Lipase|the enzymes that digest fat]]. As a result, some fat cannot be absorbed from the gut and is excreted in the feces instead of being metabolically digested and absorbed, sometimes causing oily anal leakage.<ref name=WP>{{cite news |first= Sally|last= Squires|title=Weighing a Pill For Weight Loss |url=https://www.washingtonpost.com/wp-dyn/content/article/2006/01/23/AR2006012301270.html |quote=While the Food and Drug Administration (FDA) still must approve the switch, the agency often follows the advice of its experts. If it does, Orlistat (xenical) -- currently sold only by prescription -- could be available over-the-counter (OTC) later this year. But it's important to know that the weight loss that's typical for users of the drug -- 5 to 10 percent of total weight -- will be less than many dieters expect. And many consumers may be put off by the drug's significant gastrointestinal side effects, including [[flatulence]], [[diarrhea]], and anal leakage. |newspaper=[[Washington Post]] |date= 2006-01-24|access-date=2007-07-06}}</ref><ref name=CSPI>{{cite news |title=Frito-Lay Study: Olestra Causes "Anal Oil Leakage" |url=http://www.cspinet.org/new/flaynal.html |quote=The Frito-Lay report states: "The anal oil leakage symptoms were observed in this study (3 to 9% incidence range above background), as well as other changes in elimination. ... Underwear spotting was statistically significant in one of two low-level consumer groups at a 5% incidence above background." Despite those problems, the authors of the report concluded that olestra-containing snacks "should have a high potential for acceptance in the marketplace." |publisher=[[Center for Science in the Public Interest]] |date=February 13, 1997 |access-date=2007-07-07 |archive-date=2016-06-18 |archive-url=https://web.archive.org/web/20160618195225/http://www.cspinet.org/new/flaynal.html |url-status=dead }}</ref><ref name=NW>{{cite news |title=The Word Is 'Leakage'. Accidents may happen with a new OTC diet drug. |url=http://www.msnbc.msn.com/id/19263093/site/newsweek/ |quote=GlaxoSmithKline has a tip for people who decide to try Alli, the over-the-counter weight-loss drug it is launching with a multimillion-dollar advertising blitz—keep an extra pair of pants handy. That's because Alli, a lower-dose version of the prescription drug [[Xenical]], could (cue the late-night talk-show hosts) make you soil your pants. But while Alli's most troublesome side effect, anal leakage, is sure to be good for a few laughs, millions of people who are desperate to take off weight may still decide the threat of an accident is worth it. |publisher=[[Newsweek]] |date=June 25, 2007 |access-date=2007-06-21 |url-status=dead |archive-url = https://web.archive.org/web/20070618160359/http://www.msnbc.msn.com/id/19263093/site/newsweek/ <!-- Bot retrieved archive --> |archive-date = 2007-06-18}}</ref> Vytorin (ezetimibe/simvastatin) tablets can cause steatorrhea in some people.<ref name=WP/><ref name=NW/>
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