Editing Synaptic vesicle (section)

=== Vesicle pools ===
Vesicles in the nerve terminal are grouped into three pools: the readily releasable pool, the recycling pool, and the reserve pool.<ref name="Rizzoli_Betz_2005">{{cite journal|last1=Rizzoli|first1=Silvio O|last2=Betz|first2=William J|title=Synaptic vesicle pools|journal=Nature Reviews Neuroscience|date=January 2005|volume=6|issue=1|pages=57–69|pmid=15611727|doi=10.1038/nrn1583|s2cid=7473893}}</ref> These pools are distinguished by their function and position in the nerve terminal. The readily releasable pool are docked to the [[cell membrane]], making these the first group of vesicles to be released on stimulation. The readily releasable pool is small and is quickly exhausted. The recycling pool is proximate to the cell membrane, and tend to be cycled at moderate stimulation, so that the rate of vesicle release is the same as, or lower than, the rate of vesicle formation. This pool is larger than the readily releasable pool, but it takes longer to become mobilised. The reserve pool contains vesicles that are not released under normal conditions. This reserve pool can be quite large (~50%) in neurons grown on a glass substrate, but is very small or absent at mature synapses in intact brain tissue.<ref>{{Cite journal|last1=Rose|first1=Tobias|last2=Schoenenberger|first2=Philipp|last3=Jezek|first3=Karel|last4=Oertner|first4=Thomas G.|title=Developmental Refinement of Vesicle Cycling at Schaffer Collateral Synapses|journal=Neuron|volume=77|issue=6|pages=1109–1121|doi=10.1016/j.neuron.2013.01.021|pmid=23522046|year=2013|doi-access=free}}</ref><ref>{{Cite journal|last1=Xue|first1=Lei|last2=Sheng|first2=Jiansong|last3=Wu|first3=Xin-Sheng|last4=Wu|first4=Wei|last5=Luo|first5=Fujun|last6=Shin|first6=Wonchul|last7=Chiang|first7=Hsueh-Cheng|last8=Wu|first8=Ling-Gang|date=2013-05-15|title=Most Vesicles in a Central Nerve Terminal Participate in Recycling|journal=Journal of Neuroscience|volume=33|issue=20|pages=8820–8826|doi=10.1523/jneurosci.4029-12.2013|pmid=23678124|pmc=3710729}}</ref>