Editing Transfer RNA (section)

===Anticodon===
An '''anticodon'''<ref>{{cite journal | vauthors = Felsenfeld G, Cantoni GL | title = Use of thermal denaturation studies to investigate the base sequence of yeast serine sRNA | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 51 | issue = 5 | pages = 818–826 | date = May 1964 | pmid = 14172997 | pmc = 300168 | doi = 10.1073/pnas.51.5.818 | bibcode = 1964PNAS...51..818F | doi-access = free }}</ref> is a unit of three [[nucleotides]] corresponding to the three bases of an [[mRNA]] [[genetic code|codon]]. Each tRNA has a distinct anticodon triplet sequence that can form 3 [[Complementarity (molecular biology)|complementary]] [[base pair]]s to one or more codons for an amino acid. Some anticodons pair with more than one codon due to [[wobble base pair]]ing. Frequently, the first nucleotide of the anticodon is one not found on mRNA: [[inosine]], which can [[hydrogen bond]] to more than one base in the corresponding codon position.<ref name="Stryer2002" />{{rp|29.3.9}} In [[genetic code]], it is common for a single amino acid to be specified by all four third-position possibilities, or at least by both [[pyrimidine]]s and [[purine]]s; for example, the amino acid [[glycine]] is coded for by the codon sequences GGU, GGC, GGA, and GGG. Other modified nucleotides may also appear at the first anticodon position—sometimes known as the "wobble position"—resulting in subtle changes to the genetic code, as for example in [[mitochondria]].<ref>{{cite journal | vauthors = Suzuki T, Suzuki T | title = A complete landscape of post-transcriptional modifications in mammalian mitochondrial tRNAs | journal = Nucleic Acids Research | volume = 42 | issue = 11 | pages = 7346–7357 | date = June 2014 | pmid = 24831542 | pmc = 4066797 | doi = 10.1093/nar/gku390 }}</ref> The possibility of wobble bases reduces the number of tRNA types required: instead of 61 types with one for each sense codon of the standard genetic code), only 31 tRNAs are required to translate, unambiguously, all 61 sense codons.<ref name="crick" /><ref>Lodish H, Berk A, Matsudaira P, Kaiser CA, Krieger M, Scott MP, Zipursky SL, Darnell J. (2004). ''Molecular Cell Biology''. WH Freeman: New York. 5th ed.{{ISBN|978-0716743668}}{{page needed|date=April 2019}}</ref>