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Vancomycin-resistant Staphylococcus aureus
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==Treatment of infection== [[File:Rifampicin3Dan.gif|thumb|150 px|[[Rifampicin]] (''Rifampin'')]] When the [[minimum inhibitory concentration]] of vancomycin is {{nowrap|> 2 µg/mL}}, alternative antibiotics should be used. The approach is to treat with at least one agent to which the bacteria known to be susceptible by ''[[in vitro]]'' testing. The agents that are used include [[daptomycin]], [[linezolid]], [[telavancin]], [[ceftaroline fosamil|ceftaroline]], and [[Quinupristin/dalfopristin|quinupristin–dalfopristin]]. For people with [[Methicillin-resistant Staphylococcus aureus|methicillin-resistant ''Staphylococcus aureus'']] (MRSA) [[bacteremia]] in the setting of vancomycin failure the Infectious Diseases Society of America recommends high-dose [[daptomycin]], if the isolate is susceptible, in combination with another agent (e.g., [[gentamicin]], [[Rifampicin|rifampin]], [[linezolid]], [[trimethoprim/sulfamethoxazole]], or a [[Β-Lactam|beta-lactam]] antibiotic).<ref name="beta">{{cite journal|title=Clinical Practice Guidelines by the Infectious Diseases Society of America for the Treatment of Methicillin-Resistant Staphylococcus Aureus Infections in Adults and Children|last= Liu|first=Catherine|year=2011|volume=52|issue=3|pages=e18–e55|doi=10.1093/cid/ciq146|journal=Clinical Infectious Diseases|display-authors=etal|pmid=21208910|doi-access=free}}</ref>
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