Open main menu
Home
Random
Recent changes
Special pages
Community portal
Preferences
About Wikipedia
Disclaimers
Incubator escapee wiki
Search
User menu
Talk
Dark mode
Contributions
Create account
Log in
Editing
Winner's curse
(section)
Warning:
You are not logged in. Your IP address will be publicly visible if you make any edits. If you
log in
or
create an account
, your edits will be attributed to your username, along with other benefits.
Anti-spam check. Do
not
fill this in!
==Related uses== {{Main|Regression toward the mean}} The term ''winner's curse'' is also used in statistics to refer to the [[regression toward the mean]] phenomenon, particularly in [[genome-wide association studies]] and [[epidemiology]]. In studies involving many tests on one sample of the full population, the consequent stringent standards for significance make it likely that the first person to report a significant test (the ''winner'') will also report an [[effect size]] much larger than is likely to be seen in subsequent [[Replication (scientific method)|replication]] studies.<ref>{{cite journal |last=Ioannidis |first=John P. A. |year=2008 |title=Why most discovered true associations are inflated |journal=Epidemiology |volume=19 |issue=5 |pages=640β648 |doi=10.1097/EDE.0b013e31818131e7 |pmid= 18633328 |s2cid=15440816 |doi-access=free }}</ref><ref>{{Cite journal|last1=Palmer|first1=Cameron|last2=Peβer|first2=Itsik|date=2017-07-17|title=Statistical correction of the Winner's Curse explains replication variability in quantitative trait genome-wide association studies|journal=PLOS Genetics|language=en|volume=13|issue=7|pages=e1006916|doi=10.1371/journal.pgen.1006916|issn=1553-7404|pmc=5536394|pmid=28715421 |doi-access=free }}</ref>
Edit summary
(Briefly describe your changes)
By publishing changes, you agree to the
Terms of Use
, and you irrevocably agree to release your contribution under the
CC BY-SA 4.0 License
and the
GFDL
. You agree that a hyperlink or URL is sufficient attribution under the Creative Commons license.
Cancel
Editing help
(opens in new window)