Open main menu
Home
Random
Recent changes
Special pages
Community portal
Preferences
About Wikipedia
Disclaimers
Incubator escapee wiki
Search
User menu
Talk
Dark mode
Contributions
Create account
Log in
Editing
Wobble base pair
(section)
Warning:
You are not logged in. Your IP address will be publicly visible if you make any edits. If you
log in
or
create an account
, your edits will be attributed to your username, along with other benefits.
Anti-spam check. Do
not
fill this in!
===tRNA base pairing schemes=== Wobble pairing rules. Watson-Crick base pairs are shown in '''bold'''. Parentheses denote bindings that work but will be favoured less. A leading x denotes derivatives (in general) of the base that follows. {| class="wikitable" |- ! tRNA 5' anticodon base !! mRNA 3' codon base (Crick)<ref group=note>These relationships can be further observed, as well as full codons and anticodons in the correct reading frame at: {{cite web|last1=SBDR|title=Genetic Code and Amino Acid Translation|url=http://www.soc-bdr.org/rds/authors/unit_tables_conversions_and_genetic_dictionaries/genetic_code_tables/index_en.html|website=Society for Biomedical Diabetes Research|date=2008-04-15|access-date=2014-09-14|archive-url=https://web.archive.org/web/20141104171908/http://www.soc-bdr.org/rds/authors/unit_tables_conversions_and_genetic_dictionaries/genetic_code_tables/index_en.html|archive-date=2014-11-04|url-status=live}} For a modern view on the pairings, see doi:10.1093/nar/gkh185.</ref> !! mRNA 3' codon base (Revised)<ref>{{cite journal|last1=Murphy IV|first1=Frank V|last2=Ramakrishnan|first2=V|title=Structure of a purine-purine wobble base pair in the decoding center of the ribosome|journal=Nature Structural & Molecular Biology|date=21 November 2004|volume=11|issue=12|pages=1251β1252|doi=10.1038/nsmb866|pmid=15558050|s2cid=27022506}}</ref> |- |A || '''U''' || '''U''', C, G, or (A) |- |C || '''G''' || '''G''' |- |G || '''C''' or U || '''C''' or U |- |U || '''A''' or G || '''A''', G, U, or (C) |- |[[Hypoxanthine|I]] || A, C, or U || A, C, or U |- | [[Lysidine (nucleoside)|k<sup>2</sup>C]] || || A |- |x[[5-methyl-2-thiouridine|m<sup>5</sup>s<sup>2</sup>U]], x[[5-methyl-2'-O-methyluridine|m<sup>5</sup>Um]], [[2'-O-methyluridine|Um]], x[[5-methyluridine|m<sup>5</sup>U]] || || '''A''' or (G) |- |x[[5-hydroxyuridine|o<sup>5</sup>U]] || || U, A, or G |}
Edit summary
(Briefly describe your changes)
By publishing changes, you agree to the
Terms of Use
, and you irrevocably agree to release your contribution under the
CC BY-SA 4.0 License
and the
GFDL
. You agree that a hyperlink or URL is sufficient attribution under the Creative Commons license.
Cancel
Editing help
(opens in new window)