Editing Testosterone (section)

===Levels===
Total levels of testosterone in the body have been reported as 264 to 916&nbsp;ng/dL (nanograms per deciliter) in non-obese European and American men age 19 to 39&nbsp;years,<ref name="pmid28324103">{{cite journal | vauthors = Travison TG, Vesper HW, Orwoll E, Wu F, Kaufman JM, Wang Y, Lapauw B, Fiers T, Matsumoto AM, Bhasin S | title = Harmonized Reference Ranges for Circulating Testosterone Levels in Men of Four Cohort Studies in the United States and Europe | journal = The Journal of Clinical Endocrinology and Metabolism | volume = 102 | issue = 4 | pages = 1161–1173 | date = April 2017 | pmid = 28324103 | pmc = 5460736 | doi = 10.1210/jc.2016-2935 }}</ref> while mean testosterone levels in adult men have been reported as 630&nbsp;ng/dL.<ref name="Sperling2014" /> Although commonly used as a [[reference range]],<ref>{{cite web |title=Testosterone, total |url=https://www.labcorp.com/tests/004226/testosterone-total |website=LabCorp |access-date=20 December 2021 |archive-date=December 20, 2021 |archive-url=https://web.archive.org/web/20211220171446/https://www.labcorp.com/tests/004226/testosterone-total |url-status=live }}</ref> some physicians have disputed the use of this range to determine [[hypogonadism]].<ref>{{cite journal | vauthors = Morgentaler A | title = Andrology: Testosterone reference ranges and diagnosis of testosterone deficiency | journal = Nature Reviews. Urology | volume = 14 | issue = 5 | pages = 263–264 | date = May 2017 | pmid = 28266512 | doi = 10.1038/nrurol.2017.35 | s2cid = 29122481 }}</ref><ref>{{cite journal | vauthors = Morgentaler A, Khera M, Maggi M, Zitzmann M | title = Commentary: Who is a candidate for testosterone therapy? A synthesis of international expert opinions | journal = The Journal of Sexual Medicine | volume = 11 | issue = 7 | pages = 1636–1645 | date = July 2014 | pmid = 24797325 | doi = 10.1111/jsm.12546 }}</ref> Several professional medical groups have recommended that 350&nbsp;ng/dL generally be considered the minimum normal level,<ref>{{cite journal | vauthors = Wang C, Nieschlag E, Swerdloff R, Behre HM, Hellstrom WJ, Gooren LJ, Kaufman JM, Legros JJ, Lunenfeld B, Morales A, Morley JE, Schulman C, Thompson IM, Weidner W, Wu FC | title = ISA, ISSAM, EAU, EAA and ASA recommendations: investigation, treatment and monitoring of late-onset hypogonadism in males | journal = International Journal of Impotence Research | volume = 21 | issue = 1 | pages = 1–8 | date = 16 October 208 | pmid = 18923415 | doi = 10.1038/ijir.2008.41 | s2cid = 30430279 | url = https://biblio.ugent.be/publication/631584/file/741306 | url-access = subscription }}</ref> which is consistent with previous findings.<ref>{{cite journal | vauthors = Bhasin S, Pencina M, Jasuja GK, Travison TG, Coviello A, Orwoll E, Wang PY, Nielson C, Wu F, Tajar A, Labrie F, Vesper H, Zhang A, Ulloor J, Singh R, D'Agostino R, Vasan RS | title = Reference ranges for testosterone in men generated using liquid chromatography tandem mass spectrometry in a community-based sample of healthy nonobese young men in the Framingham Heart Study and applied to three geographically distinct cohorts | journal = The Journal of Clinical Endocrinology and Metabolism | volume = 96 | issue = 8 | pages = 2430–2439 | date = August 2011 | pmid = 21697255 | pmc = 3146796 | doi = 10.1210/jc.2010-3012 }}</ref>{{primary source inline|date=December 2021}}{{medical citation needed|date=December 2021}} Levels of testosterone in men decline with age.<ref name="pmid28324103" /> In women, mean levels of total testosterone have been reported to be 32.6&nbsp;ng/dL.<ref name="Camacho2012">{{cite book|vauthors=Camacho PM|title=Evidence-Based Endocrinology|url=https://books.google.com/books?id=s06wXkPAnfcC&pg=PA217|date=26 September 2012|publisher=Lippincott Williams & Wilkins|isbn=978-1-4511-7146-4|pages=217–|access-date=May 19, 2018|archive-date=January 11, 2023|archive-url=https://web.archive.org/web/20230111143033/https://books.google.com/books?id=s06wXkPAnfcC&pg=PA217|url-status=live}}</ref><ref name="pmid15251757">{{cite journal | vauthors = Steinberger E, Ayala C, Hsi B, Smith KD, Rodriguez-Rigau LJ, Weidman ER, Reimondo GG | title = Utilization of commercial laboratory results in management of hyperandrogenism in women | journal = Endocrine Practice | volume = 4 | issue = 1 | pages = 1–10 | date = 1998 | pmid = 15251757 | doi = 10.4158/EP.4.1.1 }}</ref> In women with [[hyperandrogenism]], mean levels of total testosterone have been reported to be 62.1&nbsp;ng/dL.<ref name="Camacho2012" /><ref name="pmid15251757" />

{{Testosterone levels in males and females}}

{| class="wikitable mw-collapsible mw-collapsed" style="text-align:left; margin-left:auto; margin-right:auto; border:none;"
|+ class="nowrap" | Total testosterone levels in males throughout life
|-
! Life stage !! Tanner stage !! Age range !! Mean age !! Levels range !! Mean levels
|-
| Child || Stage I || <10 years || – || <30&nbsp;ng/dL || 5.8&nbsp;ng/dL
|-
| rowspan="4" | Puberty || Stage II || 10–14 years || 12 years || <167&nbsp;ng/dL || 40&nbsp;ng/dL
|-
| Stage III || 12–16 years || 13–14 years || 21–719&nbsp;ng/dL || 190&nbsp;ng/dL
|-
| Stage IV || 13–17 years || 14–15 years || 25–912&nbsp;ng/dL || 370&nbsp;ng/dL
|-
| Stage V || 13–17 years || 15 years || 110–975&nbsp;ng/dL || 550&nbsp;ng/dL
|-
| Adult || – || ≥18 years || – || 250–1,100&nbsp;ng/dL || 630&nbsp;ng/dL
|- class="sortbottom"
| colspan="6" style="width: 1px; background-color:#eaecf0; text-align: center;" | '''Sources:''' <ref name="BajajBerman2011">{{cite book|vauthors=Bajaj L, Berman S|title=Berman's Pediatric Decision Making|url=https://books.google.com/books?id=NPhnHrDQ1_kC&pg=PA160|date=1 January 2011|publisher=Elsevier Health Sciences|isbn=978-0-323-05405-8|pages=160–|access-date=March 25, 2018|archive-date=January 11, 2023|archive-url=https://web.archive.org/web/20230111143033/https://books.google.com/books?id=NPhnHrDQ1_kC&pg=PA160|url-status=live}}</ref><ref name="Styne2016">{{cite book|vauthors=Styne DM|title=Pediatric Endocrinology: A Clinical Handbook|url=https://books.google.com/books?id=akMWDAAAQBAJ&pg=PA191|date=25 April 2016|publisher=Springer|isbn=978-3-319-18371-8|pages=191–|access-date=March 25, 2018|archive-date=January 11, 2023|archive-url=https://web.archive.org/web/20230111143038/https://books.google.com/books?id=akMWDAAAQBAJ&pg=PA191|url-status=live}}</ref><ref name="Sperling2014">{{cite book|vauthors=Sperling MA|title=Pediatric Endocrinology E-Book|url=https://books.google.com/books?id=GgXnAgAAQBAJ&pg=PA488|date=10 April 2014|publisher=Elsevier Health Sciences|isbn=978-1-4557-5973-6|pages=488–|access-date=March 25, 2018|archive-date=January 11, 2023|archive-url=https://web.archive.org/web/20230111143036/https://books.google.com/books?id=GgXnAgAAQBAJ&pg=PA488|url-status=live}}</ref><ref name="PaganaPagana2014">{{cite book |vauthors=Pagana KD, Pagana TJ, Pagana TN |title=Mosby's Diagnostic and Laboratory Test Reference – E-Book |url=https://books.google.com/books?id=J7eXBAAAQBAJ&pg=PA879 |date=19 September 2014 |publisher=Elsevier Health Sciences |isbn=978-0-323-22592-2 |pages=879– |access-date=March 25, 2018 |archive-date=January 11, 2023 |archive-url=https://web.archive.org/web/20230111143038/https://books.google.com/books?id=J7eXBAAAQBAJ&pg=PA879 |url-status=live }}</ref><ref name="HospitalEngorn2014">{{cite book |vauthors=Engorn B, Flerlage J |title=The Harriet Lane Handbook E-Book |url=https://books.google.com/books?id=6cSLAwAAQBAJ&pg=PA240 |date=1 May 2014 |publisher=Elsevier Health Sciences |isbn=978-0-323-11246-8 |pages=240– |access-date=March 25, 2018 |archive-date=January 11, 2023 |archive-url=https://web.archive.org/web/20230111143039/https://books.google.com/books?id=6cSLAwAAQBAJ&pg=PA240 |url-status=live }}</ref>
|}

{{wide image|Blood values sorted by mass and molar concentration.png|1200px|[[Reference ranges for blood tests]], showing adult male testosterone levels in light blue at center-left}}