Editing Coagulation (section)

==Other species==
All mammals have an extremely closely related blood coagulation process, using a combined cellular and serine protease process.{{citation needed|date=October 2012}} It is possible for any mammalian coagulation factor to "cleave" its equivalent target in any other mammal.{{citation needed|date=October 2012}} The only non-mammalian animal known to use serine proteases for blood coagulation is the [[horseshoe crab]].<ref name="pmid15170505">{{Cite journal |vauthors=Osaki T, Kawabata S |date=June 2004 |title=Structure and function of coagulogen, a clottable protein in horseshoe crabs |journal=Cellular and Molecular Life Sciences |volume=61 |issue=11 |pages=1257–65 |doi=10.1007/s00018-004-3396-5 |pmc=11138774 |pmid=15170505 |s2cid=24537601}}</ref> Exemplifying the close links between coagulation and inflammation, the horseshoe crab has a primitive response to injury, carried out by cells known as amoebocytes (or [[Hemocyte (invertebrate immune system cell)|hemocytes]]) which serve both hemostatic and immune functions.<ref name="Yong23">{{Cite journal |last=Yong |first=J |last2=Toh |first2=CH |date=21 December 2023 |title=Rethinking coagulation: from enzymatic cascade and cell-based reactions to a convergent model involving innate immune activation. |journal=Blood |volume=142 |issue=25 |pages=2133–45 |doi=10.1182/blood.2023021166 |pmid=37890148 |doi-access=free}}</ref><ref name="Iwanaga">{{Cite journal |last=Iwanaga |first=S |date=May 2007 |title=Biochemical principle of Limulus test for detecting bacterial endotoxins. |journal=Proceedings of the Japan Academy. Series B, Physical and Biological Sciences |volume=83 |issue=4 |pages=110–19 |bibcode=2007PJAB...83..110I |doi=10.2183/pjab.83.110 |pmc=3756735 |pmid=24019589}}</ref>