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Preterm birth
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==== Breathing support ==== In terms of respiratory support, there may be little or no difference in the risk of death or chronic lung disease between high flow nasal cannulae (HFNC) and [[continuous positive airway pressure]] (CPAP) or nasal intermittent positive pressure ventilation (NPPV).<ref>{{cite journal | vauthors = Hodgson KA, Wilkinson D, De Paoli AG, Manley BJ | title = Nasal high flow therapy for primary respiratory support in preterm infants | journal = The Cochrane Database of Systematic Reviews | volume = 2023 | issue = 5 | pages = CD006405 | date = May 2023 | pmid = 37144837 | pmc = 10161968 | doi = 10.1002/14651858.CD006405.pub4 }}</ref> For extremely preterm babies (born before 28 weeks' gestation), targeting a higher versus a lower oxygen saturation range makes little or no difference overall to the risk of death or major disability.<ref>{{cite journal | vauthors = Askie LM, Darlow BA, Davis PG, Finer N, Stenson B, Vento M, Whyte R | title = Effects of targeting lower versus higher arterial oxygen saturations on death or disability in preterm infants | journal = The Cochrane Database of Systematic Reviews | volume = 4 | issue = 4 | pages = CD011190 | date = April 2017 | pmid = 28398697 | pmc = 6478245 | doi = 10.1002/14651858.CD011190.pub2 }}</ref> Babies born before 32 weeks have been shown to have a lower risk of death from [[bronchopulmonary dysplasia]] if they have CPAP immediately after being born, compared to receiving either supportive care or assisted ventilation.<ref>{{cite journal |last1=Subramaniam |first1=P |last2=Ho |first2=JJ |last3=Davis |first3=PG |title=Prophylactic or very early initiation of continuous positive airway pressure (CPAP) for preterm infants. |journal=The Cochrane Database of Systematic Reviews |date=18 October 2021 |volume=2021 |issue=10 |pages=CD001243 |doi=10.1002/14651858.CD001243.pub4 |pmid=34661278 |pmc=8521644 |ref=CochraneCPAP}}</ref> There is insufficient evidence for or against placing preterm stable twins in the same cot or incubator (co-bedding).<ref>{{cite journal | vauthors = Lai NM, Foong SC, Foong WC, Tan K | title = Co-bedding in neonatal nursery for promoting growth and neurodevelopment in stable preterm twins | journal = The Cochrane Database of Systematic Reviews | volume = 4 | issue = 4 | pages = CD008313 | date = April 2016 | pmid = 27075527 | pmc = 6464533 | doi = 10.1002/14651858.CD008313.pub3 }}</ref>
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