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Nicotine
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===Immune system=== Immune cells of both the [[innate|innate immune system]] and [[adaptive immune system]]s frequently express the α<sub>2</sub>, α<sub>5</sub>, α<sub>6</sub>, α<sub>7</sub>, α<sub>9</sub>, and α<sub>10</sub> [[Nicotinic acetylcholine receptor#Subunits|subunits of nicotinic acetylcholine receptors]].<ref name=":0">{{cite journal | vauthors = Fujii T, Mashimo M, Moriwaki Y, Misawa H, Ono S, Horiguchi K, Kawashima K | title = Expression and Function of the Cholinergic System in Immune Cells | journal = Frontiers in Immunology | volume = 8 | page = 1085 | date = 2017 | pmid = 28932225 | pmc = 5592202 | doi = 10.3389/fimmu.2017.01085 | doi-access = free }}</ref> Evidence suggests that nicotinic receptors which contain these subunits are involved in the regulation of [[immune function]].<ref name=":0" />
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