Editing Adipocyte (section)

===Marrow fat cells===
Marrow adipocytes are unilocular like white fat cells.  The [[marrow adipose tissue]] depot is poorly understood in terms of its physiologic function and relevance to bone health. Marrow adipose tissue expands in states of low bone density but additionally expands in the setting of obesity.<ref name=":0">{{cite journal | vauthors = Styner M, Pagnotti GM, McGrath C, Wu X, Sen B, Uzer G, Xie Z, Zong X, Styner MA, Rubin CT, Rubin J | display-authors = 6 | title = Exercise Decreases Marrow Adipose Tissue Through β-Oxidation in Obese Running Mice | journal = Journal of Bone and Mineral Research | volume = 32 | issue = 8 | pages = 1692–1702 | date = August 2017 | pmid = 28436105 | pmc = 5550355 | doi = 10.1002/jbmr.3159 }}</ref> Marrow adipose tissue response to exercise approximates that of [[white adipose tissue]].<ref name=":0" /><ref>{{cite journal | vauthors = Pagnotti GM, Styner M | title = Exercise Regulation of Marrow Adipose Tissue | journal = Frontiers in Endocrinology | volume = 7 | pages = 94 | date = 2016 | pmid = 27471493 | pmc = 4943947 | doi = 10.3389/fendo.2016.00094 | doi-access = free }}</ref><ref>{{cite journal | vauthors = Styner M, Pagnotti GM, Galior K, Wu X, Thompson WR, Uzer G, Sen B, Xie Z, Horowitz MC, Styner MA, Rubin C, Rubin J | display-authors = 6 | title = Exercise Regulation of Marrow Fat in the Setting of PPARγ Agonist Treatment in Female C57BL/6 Mice | journal = Endocrinology | volume = 156 | issue = 8 | pages = 2753–2761 | date = August 2015 | pmid = 26052898 | pmc = 4511140 | doi = 10.1210/en.2015-1213 }}</ref><ref>{{cite journal | vauthors = Styner M, Thompson WR, Galior K, Uzer G, Wu X, Kadari S, Case N, Xie Z, Sen B, Romaine A, Pagnotti GM, Rubin CT, Styner MA, Horowitz MC, Rubin J | display-authors = 6 | title = Bone marrow fat accumulation accelerated by high fat diet is suppressed by exercise | journal = Bone | volume = 64 | pages = 39–46 | date = July 2014 | pmid = 24709686 | pmc = 4041821 | doi = 10.1016/j.bone.2014.03.044 }}</ref> Exercise reduces both adipocyte size as well as marrow adipose tissue volume, as quantified by [[MRI]] or [[X-ray microtomography|μCT imaging]] of bone stained with the lipid binder [[osmium]].