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Apheresis
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=== Centrifugation variables === The centrifugation process itself has four variables that can be controlled to selectively remove desired components. The first is spin speed and bowl diameter, the second is "sit time" in centrifuge, the third is solutes added, and the fourth is not as easily controllable: plasma volume and cellular content of the donor. The result in most cases is the classic sedimented blood sample with the [[Red blood cells|RBCs]] at the bottom, the [[buffy coat]] of platelets and [[White blood cells|WBCs]] ([[lymphocytes]], [[granulocytes]], [[monocytes]]) in the middle and the plasma on top.<ref name=Vrielink23>{{cite journal |vauthors=Vrielink H, Neyrinck MM |title=Basics of apheresis and equipment |journal=Transfus Apher Sci |volume=62 |issue=2 |pages=103671 |date=April 2023 |pmid=36870905 |doi=10.1016/j.transci.2023.103671 }}</ref>
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