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Bohr effect
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=== Strength of the effect and body size === The magnitude of the Bohr effect is usually given by the slope of the <math display="inline">\log (P_{50})</math> vs <math display="inline">\text{pH}</math> curve where, [[P50 (pressure)|P<sub>50</sub>]] refers to the partial pressure of oxygen when 50% of haemoglobin's binding sites are occupied. The slope is denoted: <math display="inline">{\scriptstyle \Delta \log (P_{50}) \over \Delta \text{pH}}</math> where <math display="inline"> \Delta </math> denotes change. That is, <math display="inline">\Delta \log (P_{50})</math> denotes the change in <math display="inline">\log (P_{50})</math> and <math display="inline">\Delta \text{pH}</math> the change in <math display="inline">\text{pH}</math>. Bohr effect strength exhibits an inverse relationship with the size of an organism: the magnitude increases as size and weight decreases. For example, [[Mouse|mice]] possess a very strong Bohr effect, with a <math display="inline">{\scriptstyle \Delta \log (P_{50}) \over \Delta \text{pH}}</math> value of -0.96, which requires relatively minor changes in H<sup>+</sup> or CO<sub>2</sub> concentrations, while [[elephant]]s require much larger changes in concentration to achieve a much weaker effect <math display="inline">\left({\scriptstyle \Delta \log (P_{50}) \over \Delta \text{pH}} = -0.38\right)</math>.<ref name=":1" />
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