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Cachexia
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==Causes== [[File:Cachexia Causes.svg|thumb]] Cachexia is most commonly associated with end-stage [[cancer]], often called ''cancer cachexia.''<ref name="fearon-2002">{{cite journal |vauthors=Fearon KC, Moses AG |date=September 2002 |title=Cancer cachexia |journal=International Journal of Cardiology |volume=85 |issue=1 |pages=73β81 |doi=10.1016/S0167-5273(02)00235-8 |pmid=12163211}}</ref> Other conditions that frequently cause cachexia include: * [[Congestive heart failure]] * [[AIDS]] * [[Chronic obstructive pulmonary disease]] * [[Chronic kidney disease]]<ref name="Ebner-2013">{{cite journal | vauthors = Ebner N, Springer J, Kalantar-Zadeh K, Lainscak M, Doehner W, Anker SD, von Haehling S | title = Mechanism and novel therapeutic approaches to wasting in chronic disease | journal = Maturitas | volume = 75 | issue = 3 | pages = 199β206 | date = July 2013 | pmid = 23664695 | doi = 10.1016/j.maturitas.2013.03.014 | s2cid = 42148927 | url = https://zenodo.org/record/3420540 }}{{Dead link|date=November 2023 |bot=InternetArchiveBot |fix-attempted=yes }}</ref> Cachexia can happen in late stages of diseases like [[cystic fibrosis]], [[multiple sclerosis]], [[motor neuron disease]], [[Parkinson's disease]], [[dementia]], [[tuberculosis]], [[multiple system atrophy]], [[mercury poisoning]], [[Crohn's disease]], [[trypanosomiasis]], [[rheumatoid arthritis]],[[celiac disease]], and other diseases that effect the entire body.<ref>{{cite journal | vauthors = Meresse B, Ripoche J, Heyman M, Cerf-Bensussan N | title = Celiac disease: from oral tolerance to intestinal inflammation, autoimmunity and lymphomagenesis | journal = Mucosal Immunology | volume = 2 | issue = 1 | pages = 8β23 | date = January 2009 | pmid = 19079330 | doi = 10.1038/mi.2008.75 | s2cid = 24980464 | doi-access = free }}</ref><ref>{{cite journal | vauthors = Morley JE, Thomas DR, Wilson MM | title = Cachexia: pathophysiology and clinical relevance | journal = The American Journal of Clinical Nutrition | volume = 83 | issue = 4 | pages = 735β43 | date = April 2006 | pmid = 16600922 | doi = 10.1093/ajcn/83.4.735 | doi-access = free }}</ref>
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