Editing Cell death (section)

==== Autophagy ====
Autophagy is ''[[cytoplasm]]ic'', characterized by the formation of large [[vacuole]]s that eat away [[organelle]]s in a specific sequence prior to the destruction of the [[cell nucleus|nucleus]].<ref>
{{cite journal | vauthors = Schwartz LM, Smith SW, Jones ME, Osborne BA | title = Do all programmed cell deaths occur via apoptosis? | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 90 | issue = 3 | pages = 980–984 | date = February 1993 | pmid = 8430112 | pmc = 45794 | doi = 10.1073/pnas.90.3.980 | doi-access = free | bibcode = 1993PNAS...90..980S }};and, for a more recent view, see {{cite journal | vauthors = Bursch W, Ellinger A, Gerner C, Fröhwein U, Schulte-Hermann R | title = Programmed cell death (PCD). Apoptosis, autophagic PCD, or others? | journal = Annals of the New York Academy of Sciences | volume = 926 | issue = 1 | pages = 1–12 | year = 2000 | pmid = 11193023 | doi = 10.1111/j.1749-6632.2000.tb05594.x | s2cid = 27315958 | bibcode = 2000NYASA.926....1B }}</ref> [[Macroautophagy]], often referred to as [[autophagy]], is a [[catabolic]] process that results in the [[Autophagosome|autophagosomic]]-[[Lysosome|lysosomal]] degradation of bulk [[cytoplasm]]ic contents, abnormal protein aggregates, and excess or damaged [[organelle]]s. Autophagy is generally activated by conditions of [[nutrient]] deprivation but has also been associated with [[Physiology|physiolog]]ical as well as [[Pathology|patholog]]ical processes such as development, differentiation, [[neurodegenerative]] [[disease]]s, [[stress (physiology)|stress]], [[infection]] and [[cancer]].