Editing Cold-stimulus headache (section)

==Research==
Due to how shortlived the headache is, researchers like Amokrane Chebini and Esma Dilli have voiced how difficult it is to study the phenomenon.<ref>{{cite journal |last1=Chebini |first1=Amokrane |last2=Dilli |first2=Esma |title=Cold Stimulus Headache |journal=Curr Neurol Neurosci Rep |date=June 2019 |volume=19 |issue=46 |page=46 |doi=10.1007/s11910-019-0956-5 |pmid=31172287 |url=https://rdcu.be/d06bs |access-date=22 November 2024|url-access=subscription }}</ref> Thus, there is not much research that has been conducted on the topic.

The phenomenon is common enough to have been the subject of research published in the ''[[British Medical Journal]]'' and ''[[Scientific American]]''.<ref name="sa"/><ref name="bmj"/> A study conducted by Maya Kaczorowski demonstrated a higher incidence of headache in subjects consuming an ice cream sample quickly, in less than five seconds, vs. those who consumed slowly, taking longer than thirty seconds (27% and 12%, respectively).<ref name="ICE-H" />

According to research conducted by Nigel Bird, [[Anne MacGregor]], and Marcia I. Wilkinson published in the journal ''[[Headache (journal)|Headache]]'', "17% of the migraine patients and 46% of the students developed headache following palatal application or a swallow of ice cream."<ref name="Bird92">{{cite journal |last1=Bird |first1=Nigel |last2=MacGregor |first2=Anne |last3=Wilkinson |first3=Marcia I. |year=1992 |title=Ice cream headache–site, duration, and relationship to migraine |journal=[[Headache (journal)|Headache]] |volume=32 |issue=1 |pages=35–8 |publisher=[[Wiley-Blackwell]] |doi= 10.1111/j.1526-4610.1992.hed3201035.x|pmid=1555929|s2cid=45688979 }}</ref>

According to research conducted by Ilaria Bonemazzi and several other colleagues found that the children participants in their study were more likely to develop cold-stimulus headaches compared to their adult counterparts.<ref>{{cite journal |last1=Bonemazzi |first1=Ilaria |last2=Pelizza |first2=Maria Federica |last3=Berti |first3=Giulia |last4=Ancona |first4=Claudio |last5=Nosadini |first5=Margherita |last6=Sartori |first6=Stefano |last7=Toldo |first7=Irene |title=Cold-Stimulus Headache in Children and Adolescents |journal=Life |date=April 2023 |volume=13 |issue=4 |page=973 |doi=10.3390/life13040973 |doi-access=free |pmid=37109502 |pmc=10144624 }}</ref> This may suggest that children are more sensitive to cold-stimulus headaches, and that children grow a resistance to these headaches as they grow into adults.

Cold-stimulus headaches are not always caused by consuming ice cream and other cold foods similar to it; it has been found that simply being in a colder environment may trigger the same symptoms associated with a cold-stimulus headache. In a letter written by SK Jankelowitz and AS Zagami, the authors describe a patient who experienced cold-stimulus headache symptoms while she was ice skating. <ref>{{cite journal |last1=Jankelowitz |first1=SK. |last2=Zagami |first2=AS. |date=Dec 2001 |title=Cold-stimulus headache. |journal=Cephalalgia |doi=10.1046/j.1468-2982.2001.00301.x |pmid=11843876 |volume=21 |issue=10 |page=1002|s2cid=28861589 |doi-access=free }}</ref>

In research conducted by Anthony Khoo, Michelle Kiley, and Peter J Goadsby, it was found that naproxen was seen to prevent the symptoms of a cold-stimulus headache when it was taken thirty minutes before the exposure and ingestion of a cold substance. <ref>{{cite journal |last1=Khoo |first1=Anthony |last2=Kiley |first2=Michelle |last3=Goadsby |first3=Peter J |title=Managing external cold-stimulus headache with preventive naproxen |journal=Cephalalgia Reports |date=April 2020 |volume=3 |issue=4 |doi=10.1177/2515816320915696 |doi-access=free }}</ref>