Editing Computational neuroscience (section)

=== Modeling Neuron-glia interactions ===
Glial cells participate significantly in the regulation of neuronal activity at both the cellular and the network level. Modeling this interaction allows to clarify the [[potassium cycle]],<ref>{{Cite web |title=Dynamics of Ion Fluxes between Neurons, Astrocytes and the Extracellular Space during Neurotransmission |url=https://cyberleninka.ru/article/n/dynamics-of-ion-fluxes-between-neurons-astrocytes-and-the-extracellular-space-during-neurotransmission/viewer |access-date=2023-03-14 |website=cyberleninka.ru}}</ref><ref>{{Cite journal |last1=Sibille |first1=Jérémie |last2=Duc |first2=Khanh Dao |last3=Holcman |first3=David |last4=Rouach |first4=Nathalie |date=2015-03-31 |title=The Neuroglial Potassium Cycle during Neurotransmission: Role of Kir4.1 Channels |journal=PLOS Computational Biology |language=en |volume=11 |issue=3 |pages=e1004137 |doi=10.1371/journal.pcbi.1004137 |issn=1553-7358 |pmc=4380507 |pmid=25826753|bibcode=2015PLSCB..11E4137S |doi-access=free }}</ref> so important for maintaining homeostasis and to prevent epileptic seizures.  Modeling reveals the role of glial protrusions that can penetrate in some cases the synaptic cleft to interfere with the synaptic transmission and thus control synaptic communication.<ref>{{Cite journal |last1=Pannasch |first1=Ulrike |last2=Freche |first2=Dominik |last3=Dallérac |first3=Glenn |last4=Ghézali |first4=Grégory |last5=Escartin |first5=Carole |last6=Ezan |first6=Pascal |last7=Cohen-Salmon |first7=Martine |last8=Benchenane |first8=Karim |last9=Abudara |first9=Veronica |last10=Dufour |first10=Amandine |last11=Lübke |first11=Joachim H. R. |last12=Déglon |first12=Nicole |last13=Knott |first13=Graham |last14=Holcman |first14=David |last15=Rouach |first15=Nathalie |date=April 2014 |title=Connexin 30 sets synaptic strength by controlling astroglial synapse invasion |url=https://www.nature.com/articles/nn.3662 |journal=Nature Neuroscience |language=en |volume=17 |issue=4 |pages=549–558 |doi=10.1038/nn.3662 |pmid=24584052 |s2cid=554918 |issn=1546-1726}}</ref>