Editing Demodex (section)

====Research====
Research about human infestation by ''Demodex'' mites is ongoing:<ref>{{cite journal |first1=Jingbo |last1=Liu |first2=Hosam |last2=Sheha | first3=Scheffer C. G. |last3=Tseng |date=October 2010 |title=Pathogenic role of ''Demodex'' mites in blepharitis |journal=[[Current Opinion in Allergy and Clinical Immunology]] |volume=10 |issue=5 |pages=505–510 |pmid=20689407 |pmc=2946818 |doi=10.1097/ACI.0b013e32833df9f4}}</ref><ref name=yzhaocase>{{cite journal |first1=Ya-e |last1=Zhao | first2=Yan |last2=Peng |first3=Xiang-lan |last3=Wang |first4=Li-ping |last4=Wu |first5=Mei |last5=Wang |first6=Hu-ling |last6=Yan |first7=Sheng-xiang |last7=Xiao |date=December 2011 |title=Facial dermatosis associated with ''Demodex'': a case-control study |journal=[[Journal of Zhejiang University Science B]] |volume=12 |issue=8 |pages=1008–1015 |pmid=22135150 |doi=10.1631/jzus.B1100179 |pmc=3232434}}</ref><ref name="yzhaometa" /><ref name=nottinghamreview>{{cite web |publisher=University of Nottingham Centre of Evidence Based Dermatology |year=2012 |title=2011-2012 Annual Evidence Update on Acne vulgaris |page=10 |url=
http://www.nottingham.ac.uk/research/groups/cebd/documents/methodological-resources/2012-annual-evidence-update-on-acne-vulgaris.pdf |access-date=23 September 2013}}</ref>

* Evidence of a correlation between ''Demodex'' infestation and [[acne vulgaris]] exists, suggesting it may play a role in promoting acne, including in immunocompetent infants displaying [[pityriasis]] and [[erythema toxicum neonatorum]], or simply that ''Demodex'' mites thrive in the same oily conditions where acne bacteria thrive.<ref name=yzhaometa>{{cite journal |first1=Ya-e |last1=Zhao | first2=Li |last2=Hu |first3=Li-ping |last3=Wu |first4=Jun-xian |last4=Ma |date=March 2012 |title=A meta-analysis of association between acne vulgaris and ''Demodex'' infestation |journal=[[Journal of Zhejiang University Science B]] |volume=13 |issue=3 |pages=192–202 |pmid=22374611 |doi=10.1631/jzus.B1100285 |pmc=3296070}}</ref><ref>{{cite journal |last1=Douglas |first1=Annyella |last2=Zaenglein |first2=Andrea L. |title=A case series of demodicosis in children |journal=Pediatric Dermatology |date=September 2019 |volume=36 |issue=5 |pages=651–654 |doi=10.1111/pde.13852 |pmid=31197860 |s2cid=189817759 |quote=Papulopustular lesions predominate, prompting the advice 'pustules on noses, think demodicosis!'}}</ref>
* Several preliminary studies suggest an association between mite infestation and [[rosacea]].<ref name="MacKenzie">{{cite journal |first=Debora |last=MacKenzie |date=August 30, 2012 |url=https://www.newscientist.com/article/dn22227-rosacea-may-be-caused-by-mite-faeces-in-your-pores.html |title=Rosacea may be caused by mite faeces in your pores |access-date=August 30, 2012 |journal=[[New Scientist]]}}</ref><ref>{{cite journal |last1=Jarmuda |first1=Stanisław |last2=O'Reilly |first2=Niamh |last3=Żaba |first3=Ryszard |last4=Jakubowicz |first4=Oliwia |last5=Szkaradkiewicz |first5=Andrzej |last6=Kavanagh |first6=Kevin |title=Potential role of ''Demodex'' mites and bacteria in the induction of rosacea |journal=Journal of Medical Microbiology |date=1 November 2012 |volume=61 |issue=11 |pages=1504–1510 |doi=10.1099/jmm.0.048090-0 |pmid=22933353 |doi-access=free }}</ref>
*''Demodex'' mites can cause [[blepharitis]], which can be treated with solutions of [[tea tree oil]];<ref>{{Cite journal |last1=Liu |first1=Jingbo |last2=Sheha |first2=Hosam |last3=Tseng |first3=Scheffer CG |date=2010 |title=Pathogenic role of ''Demodex'' mites in blepharitis |url=https://journals.lww.com/co-allergy/Abstract/2010/10000/Pathogenic_role_of_Demodex_mites_in_blepharitis.16.aspx |journal=Current Opinion in Allergy and Clinical Immunology |language=en-US |volume=10 |issue=5 |pages=505–510 |doi=10.1097/ACI.0b013e32833df9f4 |issn=1528-4050 |pmc=2946818 |pmid=20689407}}</ref><ref>{{cite journal |last1=Zhu |first1=Minyi |last2=Cheng |first2=Chao |last3=Yi |first3=Haisu |last4=Lin |first4=Liping |last5=Wu |first5=Kaili |title=Quantitative Analysis of the Bacteria in Blepharitis With Demodex Infestation |journal=Frontiers in Microbiology |date=31 July 2018 |volume=9 |pages=1719 |doi=10.3389/fmicb.2018.01719 |pmid=30108572 |pmc=6079233 |doi-access=free }}</ref> there is no good evidence for its effectiveness.<ref>{{cite journal |last1=Savla |first1=Keyur |last2=Le |first2=Jimmy T |last3=Pucker |first3=Andrew D |title=Tea tree oil for Demodex blepharitis |journal=The Cochrane Database of Systematic Reviews |date=9 June 2019 |volume=2019 |issue=6 |pages=CD013333 |doi=10.1002/14651858.CD013333 |pmc=6556368 }}</ref>
* ''Demodex'' mites causing a reaction in healthy individuals depends on genealogy. Mites may evolve differently with different bloodlines.<ref>{{cite journal |last1=Palopoli |first1=Michael F. |last2=Fergus |first2=Daniel J. |last3=Minot |first3=Samuel |last4=Pei |first4=Dorothy T. |last5=Simison |first5=W. Brian |last6=Fernandez-Silva |first6=Iria |last7=Thoemmes |first7=Megan S. |last8=Dunn |first8=Robert R. |last9=Trautwein |first9=Michelle |title=Global divergence of the human follicle mite ''Demodex folliculorum'': Persistent associations between host ancestry and mite lineages |journal=Proceedings of the National Academy of Sciences |date=29 December 2015 |volume=112 |issue=52 |pages=15958–15963 |doi=10.1073/pnas.1512609112 |pmid=26668374 |pmc=4703014 |bibcode=2015PNAS..11215958P |doi-access=free}}
*{{cite press release |date=December 14, 2015 |title=Scientists say face mites evolved alongside humans since the dawn of human origins |website=ScienceDaily |url=https://www.sciencedaily.com/releases/2015/12/151214165733.htm}}</ref><ref>{{cite journal |last1=Bisbee |first1=E |last2=Rudnick |first2=E |last3=Loyd |first3=A |title=Crusted demodicosis in an immunocompetent patient |journal=Cutis |date=October 2019 |volume=104 |issue=4 |pages=E9–E11 |pmid=31774896 }}</ref>
* New studies suggest ''Demodex'' mites are involved in psoriasis, allergic rhinitis, and seborrheic dermatitis in immunosuppressed individuals.<ref>{{cite journal |
last1= Yengil |first1=Erhan |last2= Cevik |first2=Cengiz |last3=Aycan Kaya |first3= Özlem |last4= Taner |first4= Melis |last5=Akkoca |first5=Ayse |last6=Ozer |first6=Cahit |date=1 January 2014 |pages= 27–31 |title= Relationship between ''Demodex folliculorum'' and allergic rhinitis in adults |volume= 30 |journal= Acta Medica Mediterranea |url= https://www.researchgate.net/publication/288367546}}</ref><ref>{{cite journal |url= https://pubmed.ncbi.nlm.nih.gov/24314384/ |vauthors=Ramos-e-Silva M, Sampaio AL, Carneiro S |title= Red face revisited: Endogenous dermatitis in the form of atopic dermatitis and seborrheic dermatitis |journal=Clin. Dermatol. |year=2014  |volume=32 |issue=1 |pages=109–15 |doi= 10.1016/j.clindermatol.2013.05.032 |pmid= 24314384 }}</ref><ref>{{cite journal |title=Allergic Rhinitis and Asthma Among Adolescents with Psoriasis: A Population-based Cross-sectional Study |author1=Eran Galili |author2=Aviv Barzilai |author3=Gilad Twig |author4=Tomm Caspi |author5=Danny Daniely |author6=Rony Shreberk-Hassidim |author7=Nadav Astman|journal=Acta Dermato Venereologica |year=2020 |volume=100 |issue=10 |pages=adv00133-5 |doi=10.2340/00015555-3485 |pmid=32314795 |pmc=9137373 }}</ref>
* Atopic triad is widely known as atopic dermatitis, allergic rhinitis and asthma."<ref>{{cite book |url=https://www.ncbi.nlm.nih.gov/books/NBK448071/ |title=Atopic Dermatitis |vauthors=Kolb L, Ferrer-Bruker SJ |year=2023 |publisher=Affiliations 1 VCOM/Orange Park Medical Center Copyright © 2022, StatPearls Publishing LLC.|pmid=28846349 }}</ref>

Consequently, it has been suggested that effective management of atopic dermatitis could deter the progression of the atopic march, therefore preventing or at least reducing the subsequent development of asthma and allergic rhinitis.<ref>{{cite journal |author1=Belgrave, Danielle C M |author2=Simpson, Angela |author3=Buchan, Iain E |author4=Custovic, Adnan |title=Atopic Dermatitis and Respiratory Allergy: What is the Link |journal=Current Dermatology Reports |volume= 4 |issue=4 |year=2015 |pages= 221–227 |doi=10.1007/s13671-015-0121-6|pmid=26566461 |pmc=4635175 }}</ref>