Editing Factor VII (section)

== Role in disease ==
{{main|Factor VII deficiency}}
[[Factor VII deficiency]] (congenital proconvertin deficiency) is rare and inherited recessively.  It presents as a hemophilia-like bleeding disorder.  It is treated with recombinant factor VIIa (NovoSeven or [[AryoSeven]]). Gene therapy approaches for treating FVII deficiency are very promising (<ref>{{cite journal | vauthors = Marcos-Contreras OA, Smith SM, Bellinger DA, Raymer RA, Merricks E, Faella A, Pavani G, Zhou S, Nichols TC, High KA, Margaritis P | display-authors = 6 | title = Sustained correction of FVII deficiency in dogs using AAV-mediated expression of zymogen FVII | journal = Blood | volume = 127 | issue = 5 | pages = 565–571 | date = February 2016 | pmid = 26702064 | pmc = 4742547 | doi = 10.1182/blood-2015-09-671420 }}</ref>)