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===Ploidy=== Most eukaryotes are [[Ploidy|diploid]], meaning that there are two of each chromosome in the nucleus but the 'genome' refers to only one copy of each chromosome. Some eukaryotes have distinctive sex chromosomes, such as the X and Y chromosomes of mammals, so the technical definition of the genome must include both copies of the sex chromosomes. For example, the standard reference genome of humans consists of one copy of each of the 22 autosomes plus one X chromosome and one Y chromosome.<ref>{{cite web |url = https://useast.ensembl.org/Homo_sapiens/Info/Annotation |title = Ensembl Human Assembly and gene annotation (GRCh38) |publisher = Ensembl |access-date = May 30, 2022}}</ref>
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